Results 81 to 90 of about 696,285 (263)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Performance Analysis of a GAX Absorption Cycle with Ionic Liquid-water Working Pairs

open access: yesZhileng xuebao, 2019
Heat-driven absorption refrigeration technology is an important approach for solar-energy utilization and industrial-waste heat recovery. Among them, the generation and absorption heat exchange (GAX) absorption cycle exhibits a high efficiency whose ...
Zhao Xinrui, Xu Zhenyuan, Wang Ruzhu
doaj  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Alteration of Water Absorption Coefficient of Spruce (Picea abies (L.) Karst.) due to Thermal Modification

open access: yesDrvna Industrija, 2011
The aim of the investigations was to evaluate the infl uence of a thermal modifi cation on the water absorption behaviour of spruce (Picea abies(L.) Karst.).
Alexander Pfriem
doaj  

Effects of Potassium Supply in Nutrient Solution on Water and Nutrient Absorption of Substrate-Grown Tomato Plants

open access: yesHorticulturae
Potassium (K+) functions as a critical “regulator” and “quality element” in plants, with its physiological roles varying across developmental stages. To clarify the effects of different K+ amounts in nutrient solution on water and nutrient absorption ...
Jinxiu Song   +6 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Nanoporosity improved water absorption, in vitro degradability, mineralization, osteoblast responses and drug release of poly(butylene succinate)-based composite scaffolds containing nanoporous magnesium silicate compared with magnesium silicate

open access: yesInternational Journal of Nanomedicine, 2017
Zhaoying Wu,1 Quan Li,2 Yongkang Pan,1 Yuan Yao,1 Songchao Tang,1 Jiacan Su,2 Jung-Woog Shin,3 Jie Wei,1 Jun Zhao4,5 1Key Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, 2Department of ...
Wu Z   +8 more
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Water absorption characteristics of wood: errors and improvements in water absorption testing

open access: yesMaterials and Structures
Abstract Wood exhibits absorption characteristics that deviate from theories that have conventionally been applied to liquid transport in porous building materials, leading to difficulties in interpreting experimental results and determining the essential hygric properties of wood.
openaire   +2 more sources

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