Results 41 to 50 of about 29,108,569 (288)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Journal of Veterinary Research, 2020 Contamination by Staphylococcus aureus of food produced from animal sources may have diverse and multifactorial causes that depend on geographical distribution. The goal of this study was to isolate and characterise S.
Sankomkai Wanwisa +6 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Green Processing and Synthesis, 2019 The preparation of magnetic solid adsorbents for solid phase extraction often involved time-consuming stepwise reaction and high-temperature reaction. In this study, the coating of silica and the functionalization of magnetite were performed in a single ...
Faraj Benrabha Abdulhadi Muftah +1 more
doaj +1 more source
, 2021 This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water, Public Water Supply Section
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
ChemosensorsThe sensing of surfactants is a topic of interest for industrial and environmental purposes. Polydopamine-coated magnetite (Fe3O4@PDA) can be a relevant support for the detection of cationic surfactants in water samples.
Alberto Fernández-Núñez +4 more
doaj +1 more source
, 2022 This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water, Public Water Supply Section
core