Results 71 to 80 of about 7,600,223 (297)

Water availability for Oregon's rivers and streams [PDF]

, 1991
Volume 1. Overview -- Volume 2. Technical Guide and Appendixes.Title from PDF cover (viewed on November 20, 2018).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Local water use and climate variability drive water stress and alter ecological flows over the conterminous United States

Environmental Research: Water
Consistent, large-scale estimates of water availability are needed to identify and avoid potential conflicts among human and ecosystem uses of water. We present an assessment of water limitation, defined as the monthly balance (difference) between water ...
E G Stets, M J Cashman, O Miller, K A Powlen, A J Martinez, J Padilla, A A Archer   +6 more
doaj   +1 more source

Socio-economic Impacts of Community-based Rehabilitation of Degraded Lands: Evidence from North Showa Zone, Oromia-Ethiopia

Indonesian Journal of Social and Environmental Issues
A large part of research to date is devoted to the rehabilitation of degraded landscapes focused on technical aspects. This paper evaluated the socio-economic outcomes of Community-Based Rehabilitation of Degraded Land (CBRDL) in the North Showa area of ...
Alemtsehaye Ferede, Alemayehu Ayana
doaj   +1 more source

Water in the 2010 Virginia General Assembly

, 2010
The 2010 Virginia General Assembly convened January 13 and adjourned March 13. The reconvened (“veto”) session was held April 21. During the session, the Assembly considered 2964 measures, passing 1598 of them, defeating 1093, and continuing 273 until ...
Virginia Water Resources Research Center
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Water in the 2006 Virginia General Assembly

, 2006
The 2006 Virginia General Assembly convened January 11 and adjourned March 11, with a reconvened (“veto”) session on April 19. The legislature considered 3287 measures; among the most important business was development of the biennial state budget. Below
Virginia Water Resources Research Center
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Water-Related Bills in the 2008 Virginia General Assembly

, 2008
The 2008 Virginia General Assembly session opened January 9 and adjourned March 13. Work on the biennial state budget required a few additional days beyond the scheduled adjournment date of March 8.
Virginia Water Resources Research Center
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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source