Results 101 to 110 of about 1,575,779 (255)

Identification of Loop D Domain Amino Acids in the Human Aquaporin-1 Channel Involved in Activation of the Ionic Conductance and Inhibition by AqB011

Frontiers in Chemistry, 2018
Aquaporins are integral proteins that facilitate the transmembrane transport of water and small solutes. In addition to enabling water flux, mammalian Aquaporin-1 (AQP1) channels activated by cyclic GMP can carry non-selective monovalent cation currents,
Mohamad Kourghi, Michael L. De Ieso, Saeed Nourmohammadi, Jinxin V. Pei, Andrea J. Yool   +4 more
doaj   +1 more source

Classical aspects of Hawking radiation verified in analogue gravity experiment

, 2013
There is an analogy between the propagation of fields on a curved spacetime and shallow water waves in an open channel flow. By placing a streamlined obstacle into an open channel flow we create a region of high velocity over the obstacle that can ...
A. Einsten, C. Barceló, C. Barceló, E.W. Tedford, G. Rousseaux, G. Rousseaux, G.A. Lawrence, H.A. Haus, K.V. Kheruntsyan, R. Brout, R. Schützhold, R.J. Adrian, S. Corley, S.B. Carr, S.W. Hawking, T. Jacobson, W.G. Unruh, W.G. Unruh, W.G. Unruh, W.G. Unruh, W.G. Unruh   +20 more
core   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Facilitating Water Permeation in Graphene Oxide Membranes via Incorporating Sulfonato Calix[n]arenes

Membranes
Graphene oxide (GO) with its atomic thickness and abundant functional groups holds great potential in molecular-scale membrane separation. However, constructing high-speed and highly selective water transport channels within GO membranes remains a key ...
Yufan Ji, Shurui Dong, Yiping Huang, Changhai Yue, Hao Zhu, Dan Wu, Jing Zhao   +6 more
doaj   +1 more source

Aquaporins: More Than Functional Monomers in a Tetrameric Arrangement

Cells, 2018
Aquaporins (AQPs) function as tetrameric structures in which each monomer has its own permeable pathway. The combination of structural biology, molecular dynamics simulations, and experimental approaches has contributed to improve our knowledge of how ...
Marcelo Ozu, Luciano Galizia, Cynthia Acuña, Gabriela Amodeo   +3 more
doaj   +1 more source

Evaluating Drought Vulnerability of Small Community Surface Water Supply Systems in the Midwest [PDF]

, 2009
This report presents approaches and data availability for evaluating the drought vulnerability of small community water supply systems in the Midwest that obtain water from surface water bodies, such as rivers, streams, natural lakes, and man-made ...
Hecht, Jory S., Knapp, H. Vernon
core  

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source

Effective charge and free energy of DNA inside an ion channel

, 2008
Translocation of a single stranded DNA (ssDNA) through an alpha-hemolysin channel in a lipid membrane driven by applied transmembrane voltage V was extensively studied recently. While the bare charge of the ssDNA piece inside the channel is approximately
B. I. Shklovskii, Jingshan Zhang, W. Saenger   +2 more
core   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

Advanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source