Results 51 to 60 of about 7,914,150 (283)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Trophic gradients of two minnow species with similar eco-type and their relations to water chemistry and multimetric biological integrity

Journal of Asia-Pacific Biodiversity, 2017
The objectives of this study were to determine tolerance ranges and trophic gradients of two fish populations of Zacco koreanus (Zk) and Zacco platypus (Zp) in relation to chemical water quality and ecological stream health, based on the biological ...
Seoyun Choi, Jeong-Ho Han, Ji-Woong Choi, Kwang-Guk An   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Assessing the impacts of vehicle wash wastewater on surface water quality through physico-chemical and benthic macroinvertebrates analyses

Water Science, 2020
Vehicle wash wastewater (VWW) contains a wide range of contaminants and discharge of such contaminated wastewater into the surface water bodies degrade water quality and affect aquatic ecosystems.
Reeta Rai, Subodh Sharma, D.B. Gurung, Bishal K. Sitaula, Ram Devi Tachamo Shah   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Strontium and boron isotope fingerprints reveal marine and crustal controls on chemistry of Arctic meltwaters

Frontiers in Earth Science
Resolving the origin and flowpaths of meltwaters in Arctic glacierized catchments, beyond the traditional atmospheric versus water-rock framework, is crucial for understanding how weathering processes evolve with glacier retreat and regulate solute ...
Ilaria Baneschi, Linda Franceschi, Matteo Salvadori, Andrea Rielli, Paolo Di Giuseppe, Andrea Spolaor, Andrea Spolaor, Enrico Biscaro, Enrico Biscaro, Warren Raymond Lee Cairns, Matteo Lelli, Matia Menichini, Brunella Raco, Federico Scoto, Sandra Trifirò, Marco Doveri, Marco Doveri, Maddalena Pennisi   +17 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Use of Hydrothermal Treatment for Anaerobic Digestion of Dairy Manure: Process, Perspectives, and Challenges

Fuels
Effective management of dairy manure is crucial for reducing environmental and public health risks. This waste material can serve as a viable source of bioenergy via anaerobic digestion.
Kalidas Mainali, Kenita Dahal, Masoud Kazem-Rostami, Shulin Chen, Manuel Garcia-Perez   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source