Results 61 to 70 of about 21,437,192 (294)

A Scalable Spin‐Coating Strategy for Mesoporous Gold Thin Films toward miRNA Detection

Advanced Science, EarlyView.
A scalable spin‐coating strategy produces uniform mesoporous Au thin films with tunable thickness and high electroactive surface area on transparent substrates. The resulting architecture enables label‐free, amplification‐free detection of ovarian cancer‐associated miRNA hsa‐miR‐200c‐3p from 1 aM to 10 pM, achieving a 1.72 aM detection limit with high ...
Aditya Ashok, Emtiaz Ahmed, Arya Vasanth, Mandy Hei Man Leung, Miharu Eguchi, Md Shahriar A. Hossain, Mostafa Kamal Masud, Carlos Salomon, Yusuke Yamauchi   +8 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Impact of oil and gas pressure on seepage field in underground water-sealed oil storage caverns

Shuili Shuiyun Gongcheng Xuebao
Underground water-sealed oil storage caverns represent an effective oil storage technology that typically employs an artificial water curtain system to maintain a stable groundwater level and prevent product leakage.
HAN Fuzhi, XI Baoping, DONG Yunsheng, ZHAO Wenzhuo, CAI Jiahao, FAN Qiang   +5 more
doaj   +1 more source

Model test system for groundwater seepage in foundation pit engineering

Yantu gongcheng xuebao, 2017
The model test system designed is in accordance with the conditions of foundation pit engineering, which can simulate the groundwater seepage. It is composed of a soil box, a drainage box, a feed-water tank, an upper water tank, a lower water tank and a ...
XUE Li-ying 1,2, YANG bin 1,2, LIU Feng-min 1,2, ZHANG Bang-fu 1,2, WANG Kun-tai 1,2
doaj   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

Advanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao, Li Peng, Xiaobin Zheng, Cong Tan, Chuang Wang, Qijiang Xiong, Weiming Chen, Zhao Yang   +7 more
wiley   +1 more source

Three-Dimensional Seepage Field Inversion Analysis and Seepage Control Effect Evaluation of Shuidishan Reservoir

Renmin Zhujiang, 2022
Moderate permeable joint zones occur at the right dam abutment of the Shuidishan reservoir,which indicates a risk of seepage damage at the right dam abutment and its downstream.To reasonably evaluate the effect of reservoir seepage control measures,we ...
PAN Yingjie, XU Jianjun, XIE Xinghua, LU Bin, ZHANG Yu, XIE Dongyi   +5 more
doaj  

In Situ Test Study on Freezing Scheme of Freeze-Sealing Pipe Roof Applied to the Gongbei Tunnel in the Hong Kong-Zhuhai-Macau Bridge

Applied Sciences, 2016
In order to solve the water sealing problem of soil between pipes of long distance curved pipe-jacked technology, Freeze-Sealing Pipe Roof (FSPR) as an innovative pre-supporting method in tunnel engineering is being applied to the Gongbei Tunnel in the ...
Xiangdong Hu, Shengjun Deng, Hui Ren
doaj   +1 more source

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source