Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Experimental Investigation of the Atmosphere-Regolith Water Cycle on Present-Day Mars. [PDF]
Vakkada Ramachandran A +2 more
europepmc +1 more source
Groundwater and the Sustainable Development Goals (SDGs) [PDF]
Groundwater is an important part of the water cycle, but this don’t reflects at all in the indicators for the Sustainable Development Goals (SDGs) of the United Nations (UN).
Chambel, António
core
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Water Cycle Bat Algorithm and Dictionary-Based Deformable Model for Lung Tumor Segmentation. [PDF]
Shetty MV, Jayadevappa D, Veena GN.
europepmc +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Determining the precise placement of hydrological stations on a simulated digital river network is crucial for constructing hydrological models applicable to process simulation, water resource management, and flood forecasting endeavors.
Kun Wang +6 more
doaj +1 more source
Multi-year observations of the high mountain water cycle in the Langtang catchment, Central Himalaya. [PDF]
Steiner JF +8 more
europepmc +1 more source
Demonstrations of Arkansas\u27 Water Management Simulator [PDF]
One of the larger stumbling blocks to comprehensive water management is the lack of public understanding of the multitude of variables that operate at the same time within the hydrologic cycle.
Mack, Leslie E.
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source

