Results 51 to 60 of about 215,408 (268)
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Conventional methods of measuring water discharge and suspended sediment concentration (e.g., water sampling and moving acoustic Doppler current profiler [ADCP]) present challenges in large tidal rivers due to temporal and spatial constraints. This study
Cong Xiao +9 more
doaj +1 more source
This paper presents the spatial distribution of liquid and solid (suspended load) discharge in the Ivaí River Basin, and its implication in the functioning of this river system.
Isabel Terezinha Leli +3 more
doaj +1 more source
EFFECT OF DIFFERENT BORDER WIDTHS, WATER DISCHARGE AND NITROGEN FERTILIZER LEVELS ON SOME IRRIGATION EFFICIENCIES AT NORTH NILE DELTA [PDF]
Two field experiments were conducted during the two growing seasons of study 2004/2005 and 2005/2006 at Sakha Agricultural Research Station Farm to study the effect of different border widths, water discharge and nitrogen fertilizer on irrigation ...
W.M. Mosalm, M.M. Saied, M.Y.S. El-Arqan
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios +5 more
wiley +1 more source
In order to determine how the subaqueous delta evolution depends on the water and sediment processes in the Yangtze Estuary, the amounts of water and sediment discharged into the estuary were studied. The results show that, during the period from 1950 to
Yun-ping Yang +3 more
doaj +1 more source
MIXING OF THERMAL DISCHARGES IN COASTAL WATERS
Mixing of thermal effluents, being discharged from thermal power plants on coastlines and which head into surface waves was investigated by analyzing extensive field and laboratory data on plume and ocean ambient conditions. Emphasis was given on the effect of waves and surf zone currents on the modifications of plume surface area and vertical ...
N. M. Ismail +3 more
openaire +2 more sources
The temperature dependence of fatigue behavior in nickel‐based superalloys is investigated through high‐resolution measurements of plastic localization. While increasing temperature reduces localization and enhances fatigue performance in René 88DT, Inconel 718 exhibits a sharp degradation at intermediate temperature due to intensified slip ...
M. Calvat +5 more
wiley +1 more source

