Results 91 to 100 of about 702,943 (310)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Central Water Management. Water Supply and Effluent Disposal

open access: yes, 2021
This entry has been realised in the framework of the H2020-MSCA-RISE-2018 project “LoGov - Local Government and the Changing Urban-Rural Interplay”. LoGov aims to provide solutions for local governments that address the fundamental challenges resulting from urbanisation.
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

THE BASICS OF MODEL FOR MARGINAL TESTING OF COSTS FOR DISPOSAL OF EXTRACTED FORMATION WATER

open access: yesRudarsko-geološko-naftni Zbornik, 2015
Formation water is extracted throughout the life of the fields of hydrocarbons together with oil and/or gas. Oil dehydration costs, as well as those of production water reinjection represent significant component in total costs at mature oil and gas ...
Josip Ivšinović, Igor Dekanić
doaj   +1 more source

Econometric Approach to Water Use Estimation in Power Plants [PDF]

open access: yes
The purpose of this paper is to examine water use estimation in hydel and thermal electric power plants in selected regions i.e. Coastal, Rayalaseema and Telangana regions of Andhra Pradesh.
Perini Praveena Sri
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Treatment of water disposal injection process by oilfield chemicals: Maintaining injectivity and environmental effects

open access: yesPetroleum Research
Oil production from hydrocarbon reservoirs is invariably accompanied by water production, which poses significant challenges to both production and injection systems, particularly due to the formation of mineral scales.
Peyman Abbasi   +2 more
doaj   +1 more source

The Economics of Water: Taking Full Account of First Use, Reuse and Return to the Environment.A Report for the Australian Water Conservation and Reuse Research Program (AWCRRP). [PDF]

open access: yes
There has been a lot of discussion about water being undervalued in Australia. The nation's attention is presently focussed on water issues with the drought of 2002 - 2003, the deepening crisis with the River Murray and water rationing in a number of ...
Darla Hatton MacDonald
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

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