Results 31 to 40 of about 702,943 (310)
Hydro-chemical modelling of in situ behaviour of bituminized radioactive waste in Boom Clay [PDF]
, 2014 The hydro-chemical (CH) interaction between swelling Eurobitum bituminized radioactive waste (BW) and Boom Clay was investigated to assess the feasibility of geological disposal for the long-term management of this waste.
Bleyen, N +6 more
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Advances in Materials Science and Engineering, 2017 The present article is focused on a phenomenological description of a polymer workpiece Equal Channel Angular Extrusion (ECAE) through 2θ-dies of Segal and Iwahashi geometries with a channel intersection angle 2θ = 105° with fixed and movable external ...
Alexander V. Perig, Nikolai N. Golodenko
doaj +1 more source
CURRENT STATE AND PROBLEMS OF DEVELOPMENT OF THE WATER MANAGEMENT IN THE SOUTH OF RUSSIA
Юг России: экология, развитие, 2017 Aim. The aim is to give a current and retrospective assessment of the state of water resources in the South of Russia and identify key problems in their use.Methods.
T. A. Shebzukhova +4 more
doaj +1 more source
Treatment of the liquid phase from the red mud disposal site of the aluminium plant in podgorica [PDF]
Hemijska Industrija, 2004 The aim of this paper was to investigate the quality of the liquid phase (water) from the red mud disposal site of the Aluminium Plant in Podgorica. Based on theoretical knowledge and experimental results, the water from the red mud disposal site was ...
Kadović Milena V. +4 more
doaj +1 more source
Reducing exposure to high levels of perfluorinated compounds in drinking water improves reproductive outcomes: evidence from an intervention in Minnesota. [PDF]
, 2020 BackgroundPer- and polyfluoroalkyl substances (PFASs) have been detected in drinking water supplies around the world and are the subject of intense regulatory debate.
Auffhammer, Maximilian +4 more
core +3 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Journal of EngineeringA theoretical study is done to treat Baghdad biomedical wastes (5.21 tons/day) using many treatment methods according to construction and maintenance costs, energy and water consumption and decreasing waste volume and mass.
Ahmed H. Hadi +4 more
doaj +1 more source
Environment International, 2022 Nanoplastics in aquatic environments may induce adverse immunotoxicity effects in fish. However, there is insufficient evidence on the visible immunotoxicity endpoints in the larval stages of fish.
Haodong Cheng +8 more
doaj +1 more source