Results 71 to 80 of about 702,943 (310)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Drilling Fluid Waste Management in Drilling for Oil and Gas Wells

open access: yesChemical Engineering Transactions, 2017
Drilling operation produces two major wastes which are produced water and drilling waste. The drilling waste must be properly managed to ensure no impact to the environment and human.
A.R. Ismail   +4 more
doaj   +1 more source

Assessment of alternative strategies for sludge disposal into deep ocean basins off Southern California [PDF]

open access: yes, 1979
The general framework of engineering alternatives for regional ocean sludge disposal is well described in a report by Raksit, and will not be repeated here.
Brooks, Norman H.   +3 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Dampak Perbaikan Air Minum pada Kesehatan Anak : Tinjauan dari Segi Kejadian Diare dan Hubungannya dengan Kebiasaan Membuang Kotoran dan Sampah [PDF]

open access: yes, 1988
A study on the health impact of improved rural water supply with piping system was done in 2 sub districts, Regency of Sumedang, West Java. An analysis was done to elaborate the health impact of improved water supply on diarrheal disease of the children ...
Gotama, I. B. (Ida)   +2 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Extraction of silymarin compounds from milk thistle (Silybum marianum) seed using hot, liquid water as the solvent [PDF]

open access: yes, 2002
High-value specialty chemicals are usually obtained from natural products by extracting with generally regarded as safe (GRAS) solvents. Because organic solvents are quite often used, high operating and disposal costs occur.
Alvarez Barreto, J. F.   +2 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Long-term creep of Beishan granite under uniaxial compression

open access: yesInternational Journal of Mining Science and Technology
Investigations into the long-term creep behavior of Beishan granite in uniaxial compression were conducted. Four levels of axial stress (60, 70, 87, and 95 MPa) were applied to rock specimens.
Chunping Wang   +6 more
doaj   +1 more source

Assessment of training needs and institutional potential of the potable water supply and disposal sector in the Kyrgyz Republic [PDF]

open access: yesBIO Web of Conferences
This article explores the issue of training needs and the institutional potential of potable water supply and disposal sector in the Kyrgyz Republic.
Zhalil Gulmira, Duishebaeva Gulzada
doaj   +1 more source

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