Results 81 to 90 of about 702,943 (310)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Mapping aquifer salinity gradients and effects of oil field produced water disposal using geophysical logs: Elk Hills, Buena Vista and Coles Levee Oil Fields, San Joaquin Valley, California. [PDF]
PLoS One, 2022 Gillespie JM +3 more
europepmc +1 more source
Solid Waste Disposal: A Choice Experiment Experience in Malaysia [PDF]
Increasing generation of solid waste requires better quality disposal options in Malaysia. Control tipping is the most commonly used complemented by sanitary landfill and incineration. This study estimates the non-market values of improved waste disposal
Othman, Jamal, Pek, Chuen Khee
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Ultimate disposal of scrubber wastes [PDF]
Part of the initial concern with using the wet scrubbers on the hypergolic propellants was the subsequential disposal of the liquid wastes. To do this, consideration was given to all possible methods to reduce the volume of the wastes and stay within the
Cohenour, B. C.
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Treatment of refinery crude oil tank sludge : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Environmental Engineering at Massey University [PDF]
, 1999 Appendix A-5 held on floppy disk. Please consult print copy in Library.The treatment and disposal of oil refinery tank sludge is a critical issue among oil refineries.
Guan Hing, Jose B
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
MicroorganismsInternational air traffic has contributed to the global spread of SARS-CoV-2 and its variants. In early 2023, wastewater-based epidemiology (WBE) has been implemented at airports as a surveillance tool to detect emerging variants at short notice.
Cristina J. Saravia +8 more
doaj +1 more source
Ground Water Pollution and Emerging Environmental Challenges of Industrial Effluent Irrigation : A Case Study of Mettupalayam Taluk, Tamilnadu [PDF]
Industrial disposal of effluents on land and subsequent pollution of groundwater and soil of surrounding farmlands is a relatively new area of research.
Prakash Nelliyat +1 more
core +1 more source