Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Bursts in water distribution systems (WDSs) lead to water wastage and negative environmental impacts. Optimizing pressure sensor placement (PSP) for effective burst detection is crucial for prompt response and adverse event mitigation.
Kun Du +5 more
doaj +1 more source
Modeling of truncated normal distribution for estimating hydraulic parameters in water distribution systems: taking nodal water demand as an example. [PDF]
Shao Y, Li K, Zhang T, Yang YJ, Chu S.
europepmc +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
The Behaviour of Haloacetic Acids in Distribution Zones in Scotland [PDF]
HAAs are the second most prevalent class of DBPs after THMs in chlorinated drinking water and are of concern due to their potential human health risk. Their concentrations in drinking water are regulated by the US Environmental Protection Agency (US EPA)
Agori, Georgia
core
Investigation of Chloramines, Disinfection Byproducts, and Nitrification in Chloraminated Drinking Water Distribution Systems. [PDF]
Abulikemu G +6 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Modeling and optimization of pressure and water age for evaluation of urban water distribution systems performance. [PDF]
Desta WM, Feyessa FF, Debela SK.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
SmartCrawler: A Size-Adaptable In-Pipe Wireless Robotic System with Two-Phase Motion Control Algorithm in Water Distribution Systems. [PDF]
Kazeminasab S, Banks MK.
europepmc +1 more source

