Results 71 to 80 of about 238,245 (272)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Physical and Chemical Properties of Fire-Affected Soils from the Sagebrush Ecosystem of the Western US: A Laboratory Study

Soil Systems
This study aims to understand the effects of wildfires in sagebrush ecosystem on soil properties by examining connections between Soil Water Repellency (SWR), reflectance, and chemistry.
Yasaman Raeofy, Vera Samburova, Markus Berli, Eden Furtak-Cole, Brad Sion, Sally Houseman, Kristine Lu, William Curtiss, Andrew J. Andrade, Bianca Martinez, Andrey Y. Khlystov, Hans Moosmüller   +11 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Aspects of energy requirements for rock drilling [PDF]

, 1974
Development of laboratory rock breakage techniques to relate energy and surface area produced by slow compression, drop hammer and stamp mill. A detailed study of laboratory rotary-percussive drilling in a wide range of rocks under different ...
Wootton, David
core  

The initial stages of cave formation: Beyond the one-dimensional paradigm

, 2010
The solutional origin of limestone caves was recognized over a century ago, but the short penetration length of an undersaturated solution made it seem impossible for long conduits to develop.
Ladd, Anthony J. C., Szymczak, Piotr
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Identifying the origin of soil water repellency at regional level using multiple soil characteristics: The White Carpathians and Myjavska pahorkatina Upland case study

Soil and Water Research, 2015
This paper evaluates the relationship between water repellency and multiple characteristics of topsoil samples belonging to seven Reference Soil Groups, taken from the area of the White Carpathians and the Myjavska pahorkatina Upland.
Lucia KOŘENKOVÁ, Ivan ŠIMKOVIC, Pavel DLAPA, Bohdan JURÁNI, Peter MATÚŠ   +4 more
doaj   +1 more source

Strength and Expansion and Deformation Characteristics of Modified Expansive Soil by Octadecylamine

Advances in Civil Engineering, 2021
Octadecylamine was used as a primary water repellent and mixed into the remodeled expansive soil, and modified expansive soils with different water contents and octadecylamine contents were configured. The water repellency level of the modified expansive
Jun-Hua Wu, Wei-Chao Ao, Mao-Sheng Wang, Jia-Ming Liu, Fang-Yuan Fu   +4 more
doaj   +1 more source

Cooperative effects in surfactant adsorption layers at water/alkane interfaces

, 2019
In the present work, the properties of dodecyl dimethyl phosphine oxide (C12DMPO) at the water/decane interface are studied and compared with those obtained earlier at the interface to hexane.
Aidarova, S., Aksenenko, E., Fainerman, V., Javadi, A., Makievski, A., Miller, R., Nikolenko, M., Sharipova, A.   +7 more
core   +1 more source

Self-organization of hydrophobic soil and granular surfaces [PDF]

, 2007
Soil can become extremely water repellent following forest fires or oil spillages, thus preventing penetration of water and increasing runoff and soil erosion. Here the authors show that evaporation of a droplet from the surface of a hydrophobic granular
Dekker L. W., F. Brian Pyatt, Glen McHale, Michael I. Newton, Neil J. Shirtcliffe, Stefan H. Doerr   +5 more
core   +1 more source