Results 61 to 70 of about 73,284 (241)

Research of deformation processes of Amu-Bukhara canal and increase of water permeability [PDF]

BIO Web of Conferences
The use of spurs and dams in the moderation of water flow, the correct direction of water supply, flow and protection of coastal areas from leaching, increase the strength of the current repair work. phase execution.
Sobirov F.Ch., Begieva Sh.B.
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Detection of Hatching Information of Meat Duck Eggs Based on Deep Learning

Animals
With the steady growth in national per capita disposable income and the pursuit of improved dietary nutrition, food consumption has become increasingly diversified [...]
Jiawen Cai, Yongsheng Li, Yi Ji, Min Xu, Zhimin Liu, Yue Wang, Huixin Wang, Enze Duan, Lianfei Huo, Yunping Liu, Yonghong Zhang, Honghua Huan, Guofeng Han, Zongchun Bai   +13 more
doaj   +1 more source

Comparative Research of Chinese and American Standards for Electro-Chlorination System in Water Treatment Plant

南方能源建设, 2019
[Introduction] Many foreign projects need to adopt American standards for design, and many engineers are not familiar with these. [Method] In order to facilitate the relevant engineer involving in foreign projects to quickly understand the differences ...
GAO Ruiying, HUANG Baolin, LIN Jianzhong
doaj   +1 more source

Geotechnology of restoration of culverts in complex ground conditions without their decommissioning [PDF]

MATEC Web of Conferences, 2019
In the article, on the basis of extensive theoretical and experimental research carried out, innovative geotechnology for repair of culverts is presented, which provides an improvement in the conditions for interaction between the body of the structure ...
Perminov Nicolay, Perminov Andrey
doaj   +1 more source

Field test facility for monitoring water/radionuclide transport through partially saturated geologic media: design, construction, and preliminary description. Appendix I. Engineering drawings [PDF]

, 1979
The engineering plans for a test facility to monitor radionuclide transport in water through partially saturated geological media are included. Drawings for the experimental set-up excavation plan and details, lysimeter, pad, access caisson, and caisson details are presented. (DC)
Phillips, S. J., Campbell, A. C., Campbell, M. D., Gee, G. W., Hoober, H. H., Schwarzmiller, K. O.   +5 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source