Results 61 to 70 of about 722,593 (299)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Research progress of leachate treatment in waste transfer station [PDF]
E3S Web of ConferencesThe garbage leachate generated by the waste transfer station has the characteristics of scattered water sources, relatively small water quantity, large fluctuations in water quality and quantity, and high concentrations of organic matter, ammonia ...
Fu Yuan, Su Dexin, Ma Sai, Xiao Yan
doaj +1 more source
Chemical and Radiochemical Constituents in Water from Wells in the Vicinity of the Naval Reactors Facility, Idaho National Engineering and Environmental Laboratory, Idaho, 1996 [PDF]
Open-File Report, 1999 The U.S. Geological Survey, in response to a request from the U.S. Department of Energy's Pittsburgh Naval Reactors Office, Idaho Branch Office (IBO), samples water from 13 wells during 1996 as part of a long-term project to monitor water quality to the Snake River Plain aquifer in the vicinity of the Naval Reactors Facility (NRF), Idaho National ...
Knobel, L. L. +3 more
openaire +3 more sources
Engineering Feasibility Study of Fire Island as a Location for a Future Correctional Facility: Final Report [PDF]
, 1986 The "Legal Factors" section appearing on page 38–50 of this report was prepared by Stephen Conn of the UAA Justice Center, School of Justice. / This report is part of the Fire Island Prison Feasibility Study, a project conducted jointly by the School
Junge, David C. +1 more
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Scientific ReportsThe water hammer protection mechanisms for long-distance gravity-fed water transmission systems under complex terrain conditions remain inadequate. Current engineering practices commonly face issues such as insufficient negative pressure protection ...
Xiaoying Zhang +3 more
doaj +1 more source
Replacing "Water Hygiene" Managemet Model with "Water Quality Engineering" Model, A Strategy for More Efficient Management of Potabale Water Supply and Distribution [PDF]
علوم و مهندسی آب و فاضلاب, 2018 Water quality is subject to judgement by three components: the protection of public health, public acceptance and impact on the acceptability and durability of facilities.
Majid Ghannadi
doaj +1 more source
Revista Ingeniería UC, 2021 This study uses the system approach as a method of describing the relations and interaction among natural and technogenic objects and the people to elaborate the basics of the methodology of creating and developing the Natural Environment-Object of ...
Vladimir L. Bondarenko +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source