Results 121 to 130 of about 4,097 (252)

Impact of water fluoridation on dental caries decline across racial and income subgroups of Brazilian adolescents. [PDF]

Epidemiol Health, 2022
Bomfim RA, Frazão P.
europepmc   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Evidence-based water fluoridation policy. [PDF]

Sci Adv
Savitz DA.
europepmc   +1 more source

Seeking community water fluoridation information on state health department websites. [PDF]

PLoS One, 2021
Maybury C, Jacob M, Flanders JM, Horowitz AM.   +3 more
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Water Fluoridation: Institutional Arrangements and Regulatory Mechanisms in Three Selected Countries. [PDF]

J Public Health Dent
Frazão P, Tavares ABS, Morris AJ, Pollick H.   +3 more
europepmc   +1 more source

Urinary Fluoride Levels among Canadians with and without Community Water Fluoridation. [PDF]

Int J Environ Res Public Health, 2021
Riddell JK, Malin AJ, McCague H, Flora DB, Till C.   +4 more
europepmc   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Municipal water fluoridation, adolescent IQ, and cognition across the life course: Evidence from the Wisconsin Longitudinal Study. [PDF]

Proc Natl Acad Sci U S A
Warren JR, Rumore G, Sicinski K, Herd P, Engelman M.   +4 more
europepmc   +1 more source

Salt Fluoridation — An Adjunct to Water Fluoridation

Journal of the California Dental Association, 2013
openaire   +2 more sources