Results 111 to 120 of about 1,431,918 (300)
Scientific ReportsGroundwater is the primary source of water for people living in rural areas, especially during seasons when surface water is contaminated or unavailable. In Colombia, people use groundwater as drinking water without additional treatment.
Boris Lora-Ariza +2 more
doaj +1 more source
Journal of Hydrology: Regional StudiesStudy region: The Yellow River Basin in China. Study focus: The hydrological cycle in the Yellow River Basin is undergoing significant changes due to the combined effects of climate change and human activities.
Dongxue Yu +9 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
wiley +1 more source
New water accounting reveals why the Colorado River no longer reaches the sea
Communications Earth & EnvironmentPersistent overuse of water supplies from the Colorado River during recent decades has substantially depleted large storage reservoirs and triggered mandatory cutbacks in water use.
Brian D. Richter +11 more
doaj +1 more source
Preprototype vapor compression distillation subsystem [PDF]
A three-person capacity preprototype vapor compression distillation subsystem for recovering potable water from wastewater aboard spacecraft was designed, assembled, and tested.
Ellis, G. S. +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Engineering verification of the biomass production chamber [PDF]
The requirements for life support systems, both biological and physical-chemical, for long-term human attended space missions are under serious study throughout NASA.
Jones, J. D. +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Aquaponics: A Sustainable Food Production System That Provides Research Projects for Undergraduate Engineering Students [PDF]
, 2013 Aquaponics is a closed-loop, recirculating water system in which plants and fish grow together mutualistically. Aquaponics resembles a natural river or lake basin in which fish waste serves as nutrients for the plants, which in turn clean the water for ...
Cariapa, Vikram +5 more
core +1 more source