Results 171 to 180 of about 20,755 (270)

Clinical assessment of breastfeeding in preterm infants. [PDF]

Eur J Clin Nutr
Kinoshita M, White MJ, Doolan A.
europepmc   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

A non-contact wearable device for monitoring epidermal molecular flux. [PDF]

Nature
Shin J, Song JW, Flavin MT, Cho S, Li S, Tan A, Pyun KR, Huang AG, Wang H, Jeong S, Madsen KE, Trueb J, Kim M, Nguyen K, Yang A, Hsu Y, Sung W, Lee J, Phyo S, Kim JH, Banks A, Chang JK, Paller AS, Huang Y, Ameer GA, Rogers JA.   +25 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Breast Milk Intake from 1 to 8.5 Months of Lactation in the Multisite Mothers, Infants and Lactation Quality (MILQ) Study. [PDF]

Adv Nutr
Moore SE, Devi S, Kurpad A, Peerson JM, Christensen SH, Islam MM, Kac G, Michaelsen KF, Silva GT, Allen LH, MILQ Study Consortium.   +10 more
europepmc   +1 more source

Does the consumption of amylase-containing gruels impact on the energy intake and growth of Congolese infants ? [PDF]

, 2003
Allen, Cohen, Cornu, Delpeuch, Delpeuch, Donnen, F Mbemba, Golden, Gopaldas, Gopaldas, John, Lukmanji, M Moursi, Martin-Prével, Meeks Gardner, Mosha, Rahman, S Trèche, Sanchez-Grinãn, Souci, Thompson, Waterlow   +21 more
core   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Enhancing Quality of Life and Emotional Well-Being in Atopic Dermatitis Patients: Clinical Evidence of a Dermocosmetic Lipid-Replenishing Regimen. [PDF]

J Cosmet Dermatol
Gaudin M, Geoffroy A.
europepmc   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Severe acute kidney injury after near-drowning in a healthy adult: A case report. [PDF]

Medicine (Baltimore)
Xu J, Zhu B.
europepmc   +1 more source