Results 61 to 70 of about 8,866,732 (284)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Modeling of Osmotic Dehydration of Apples in Sugar Alcohols and Dihydroxyacetone (DHA) Solutions

Foods, 2019
The purpose of this paper is twofold: on the one hand, we verify effectiveness of alternatives solutes to sucrose solution as osmotic agents, while on the other hand we intend to analyze modeling transfer parameters, using different models.
Joanna Cichowska, Adam Figiel, Lidia Stasiak-Różańska, Dorota Witrowa-Rajchert   +3 more
doaj   +1 more source

Arizona department of water resources: Securing Arizona\u27s water future

, 1998
The Arizona Department of Water Resources works to secure long-term dependable water supplies for Arizona\u27s communities. The Department: administers and enforces Arizona\u27s groundwater code, and surface water rights laws (except those related to ...
Arizona Department of Water Resources
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The Development of a Uniform Alginate-Based Coating for Cantaloupe and Strawberries and the Characterization of Water Barrier Properties

Foods, 2019
Water loss, gain or transfer results in a decline in the overall quality of food. The aim of this study was to form a uniform layer of sodium alginate-based edible coating (1.25% sodium alginate, 2% glycerol, 0.2% sunflower oil, 1% span 80, 0.2% tween 80,
Tugce Senturk Parreidt, Martina Lindner, Isabell Rothkopf, Markus Schmid, Kajetan Müller   +4 more
doaj   +1 more source

Comparative Study on the Effect of Different Horizontal Ventilation Ways to Cooling and Keeping Water

Liang you shipin ke-ji, 2020
To understand the cooling effect and water loss of different transverse ventilation modes, Cover the grain stack with film and step by step unwinding grain stack film both in the transverse ventilation were used in the two wheat stored warehouses which ...
XU Jian-shuang, WANG Xue-zheng, AN Chao-nan, BAI Guo-wei, PENG Chao-yuan, LI Xi -yang, CHEN Feng, ZHANG jie   +7 more
doaj   +1 more source

Water in the 2003 Virginia General Assembly

, 2003
The 2003 Virginia General Assembly convened on January 8 and adjourned on February 22, with a reconvened (“veto”) session on April 2. The legislature considered 3277 measures; 1585 passed and 1692 failed. The legislature also considered amendments to the
Virginia Water Resources Research Center
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Physiological and environmental assessment of heat strain risk among welders using the predicted heat strain model

International Journal of Occupational Safety and Health
Introduction: Welders are routinely exposed to high thermal loads, increasing the risk of heat stress. Environmental indices such as the Wet-Bulb Globe Temperature (WBGT) are commonly used for assessment but do not account for individual physiological ...
Moch. Sahri, Farahul Jannah, Friska Ayu, Muslikha Nourma Rhomadhoni, Abdul Hakim Zakkiy Fasya   +4 more
doaj   +1 more source

Study the Mass Transfer Kinetics of Aloe vera Gel Cubes

Journal of Pure and Applied Microbiology, 2017
The present study was carried out to investigate the mass transfer kinetics of Aloe Vera gel cubes during osmo-convective and convective drying and its quality evaluation.
Shalini, Jaivir Singh, Ravi Kumar, Zarka Danish, Tarun Kumar, Ankit Sharma , Ankit Singh   +6 more
doaj   +1 more source