Results 61 to 70 of about 1,486,923 (264)

Physiological and environmental assessment of heat strain risk among welders using the predicted heat strain model

International Journal of Occupational Safety and Health
Introduction: Welders are routinely exposed to high thermal loads, increasing the risk of heat stress. Environmental indices such as the Wet-Bulb Globe Temperature (WBGT) are commonly used for assessment but do not account for individual physiological ...
Moch. Sahri, Farahul Jannah, Friska Ayu, Muslikha Nourma Rhomadhoni, Abdul Hakim Zakkiy Fasya   +4 more
doaj   +1 more source

The Development of a Uniform Alginate-Based Coating for Cantaloupe and Strawberries and the Characterization of Water Barrier Properties

Foods, 2019
Water loss, gain or transfer results in a decline in the overall quality of food. The aim of this study was to form a uniform layer of sodium alginate-based edible coating (1.25% sodium alginate, 2% glycerol, 0.2% sunflower oil, 1% span 80, 0.2% tween 80,
Tugce Senturk Parreidt, Martina Lindner, Isabell Rothkopf, Markus Schmid, Kajetan Müller   +4 more
doaj   +1 more source

Comparative Study on the Effect of Different Horizontal Ventilation Ways to Cooling and Keeping Water

Liang you shipin ke-ji, 2020
To understand the cooling effect and water loss of different transverse ventilation modes, Cover the grain stack with film and step by step unwinding grain stack film both in the transverse ventilation were used in the two wheat stored warehouses which ...
XU Jian-shuang, WANG Xue-zheng, AN Chao-nan, BAI Guo-wei, PENG Chao-yuan, LI Xi -yang, CHEN Feng, ZHANG jie   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Study the Mass Transfer Kinetics of Aloe vera Gel Cubes

Journal of Pure and Applied Microbiology, 2017
The present study was carried out to investigate the mass transfer kinetics of Aloe Vera gel cubes during osmo-convective and convective drying and its quality evaluation.
Shalini, Jaivir Singh, Ravi Kumar, Zarka Danish, Tarun Kumar, Ankit Sharma , Ankit Singh   +6 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Enhancing the quality of pear candies via jaggery‐based osmotic dehydration: Optimization and analysis

Future Postharvest and Food
Pear (Pyrus pyrifolia) is a healthy fruit; however, its availability is limited in certain seasons due to short shelf life. To overcome this limitation, a cost‐effective dehydration‐based preservation involving osmotic dehydration process with jaggery as
Gurpreet Dhillion, Amardeep Kour, Navjot Gupta, Padma Nath Atreya   +3 more
doaj   +1 more source

Factors affecting the mass transfer kinetics of osmotically dehydrated chayote (Sechium edule (Jacq.) Sw.)

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
The aim of this study was to apply osmotic dehydration (OD) to produce minimally processed chayote (Sechium edule (Jacq.) Swartz) slices. Thus, the effect of osmotic solution concentration, temperature, processing time, and vacuum pulse application on ...
Karina HUERTA-VERA, Adriana CONTRERAS-OLIVA, Ma. de Lourdes ARÉVALO-GALARZA, Enrique FLORES-ANDRADE, Ma. Bernardita PÉREZ-GAGO, Diana P. USCANGA-SOSA   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source