Results 111 to 120 of about 687,649 (293)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Water masses shape pico-nano eukaryotic communities of the Weddell Sea. [PDF]

Commun Biol, 2023
Flegontova O, Flegontov P, Jachníková N, Lukeš J, Horák A.   +4 more
europepmc   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Chromophoric signatures of microbial by‐products in the dark ocean

Geophysical Research Letters, 2016
Detailed examination of the absorption spectra from dark ocean samples allowed us to identify and deconvolve two distinct chromophores centered at 302 nm (UV) and 415 nm (visible) from the exponential decay curve characteristic of humic substances.
Teresa S. Catalá, Isabel Reche, Cintia L. Ramón, Àngel López‐Sanz, Marta Álvarez, Eva Calvo, Xosé A. Álvarez‐Salgado   +6 more
doaj   +1 more source

Transformation of South Pacific Water Masses in the Halmahera Sea [PDF]

BIO Web of Conferences
The Halmahera Sea is part of the eastern entry route of the Indonesian throughflow (ITF) passages. The characteristics and transformation of the South Pacific water masses are presented based on the HYCOM model (Hybrid Coordinate Ocean Model) and direct ...
Prasetyo Wahyudi, Wicaksono Ashari, Purwandana Adi, Edikusmanto, Surinati Dewi, Zheng Wang   +5 more
doaj   +1 more source

Vertical redistribution of principle water masses on the Northeast Greenland Shelf. [PDF]

Nat Commun, 2022
Gjelstrup CVB, Sejr MK, de Steur L, Christiansen JS, Granskog MA, Koch BP, Møller EF, Winding MHS, Stedmon CA.   +8 more
europepmc   +1 more source

Water Masses Characteristics at the Sanghie Talaud Entry Passage of Indonesian Throughflow Using Index Satal Data 2010 [PDF]

, 2014
Measurement of ocean physical parameters using the CTD was conducted by deep water expedition INDEX-SATAL 2010 (Indonesian Expedition Sangihe-Talaud) in July-August 2010.
Radjawane, I. M. (Ivonne), Hadipoetranto, P. P. (Paundra)   +1 more
core  

Water Masses of the Guiana Basin

Water
We present the results of our expeditionary studies of the water structure on a section across the Guiana basin in the western part of the Atlantic Ocean in January 2022. The section corresponds to almost the shortest distance between South America’s continental slope and the Mid-Atlantic Ridge.
Alexander Demidov, Kseniya Artamonova, Fedor Gippius, Sergey Dobrolyubov   +3 more
openaire   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Inventory of water masses and carbonate system from Brazilian's northeast coast: Monitoring ocean acidification. [PDF]

PLoS One, 2022
Ramos E Silva CA, Monteiro NSC, Cavalcante LM, Junior WT, Rocha Carneiro ME, Soares de Souza FE, Borges Garcia CA, Damasceno RN, de Araújo Rocha A.   +8 more
europepmc   +1 more source