Results 181 to 190 of about 419,072 (261)

Complete genome sequence of the endophytic <i>Pseudomonas bijieensis</i> BR-1-Y isolated from the roots of medicinal plant <i>Stemona japonica</i>. [PDF]

Microbiol Resour Announc
Zhang J, Li L, Dai H, Chen T, Du Y, Xie K, Yang X.   +6 more
europepmc   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

Prevalence of <i>Escherichia coli</i> and <i>Salmonella</i> spp. in Colombian Pig Production Settings: A One Health Perspective Study. [PDF]

Vet Sci
Pulido-Villamarín A, Vesga FJ, Venegas C, Rodríguez-Cordero D, Matiz-Villamil A, Barrientos I, Chamorro-Tobar IC, Caicedo JP, Ariza B, Gomez S, Bermudez LS, Carrascal-Camacho AK, Aranda-Silva M, Olaya E D.   +13 more
europepmc   +1 more source

Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses

Biotechnology Progress, EarlyView.
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing, Tomoki Igi, Daniel Strauss   +2 more
wiley   +1 more source

Growth and formaldehyde degradation of photoheterotrophic <i>Methylobacterium</i> within radiation fogs. [PDF]

mBio
Cao TTT, Herckes P, Straub D, Sarkar S, Garcia-Pichel F.   +4 more
europepmc   +1 more source

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

Biotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera, Ivan Gajic, Praveen Kusumanchi, Angela Andaluz, Gabrielle Dela Pena, Clifford A. Froelich, Elizabeth Higgins, Jennifer Johnston, Seyed Pouria Motevalian   +8 more
wiley   +1 more source

Biological Control of <i>Listeria monocytogenes</i> Growth in Fermented Buttermilk Enriched with Microfiltration Retentate. [PDF]

Foods
Śmigiel P, Kowalik J, Bielecka M.
europepmc   +1 more source

Regenerative perfusion bioreactor for biologics production with lower COGs

Biotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne, Dohyun Park, Hourieh Ahi, Jaeweon Lee, Seongkyu Yoon, Jongyoon Han   +5 more
wiley   +1 more source

Draft genome sequence of <i>Pseudomonas aeruginosa</i> MLSE01 isolated from seawater-driven microbial fuel cell. [PDF]

Microbiol Resour Announc
Shaha S, Ahmmed T, Antor MA, Reza A, Pranto BK, Keya S, Jamal MAHM.   +6 more
europepmc   +1 more source

Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α‐Mangostin: A Structure–Activity Relationship Insight

ChemFoodChem, EarlyView.
Free phenolic hydroxyl groups in the chemical structure of the natural xanthone α‐mangostin (MGT) contribute positively to achieving the anticancer profile against murine colon cancer, murine triple negative breast cancer, and human osteosarcoma cancer. ABSTRACT The α‐mangostin (MGT) is a natural xanthone obtained from the pericarp of mangosteen fruit (
Otávio Augusto Chaves, Afonso Santine M. M. Velez, Lívia Stenico, Douglas Chaves de Alcântara Pinto, Debora Decote‐Ricardo, Eliezer Avila Gandra, Marco Edilson Freire de Lima, Carlos Serpa   +7 more
wiley   +1 more source