Optimization of multi‐column chromatography for capture and polishing at high protein load
Abstract Integrated Continuous Biomanufacturing reduces manufacturing costs while maintaining product quality. A key contributor to high biopharmaceutical costs, specifically monoclonal antibodies (mAbs), is chromatography. Protein A ligands are usually preferred but still expensive in the manufacturing context, and batch chromatography under‐utilizes ...
Tiago Castanheira Silva+4 more
wiley +1 more source
Viral whole-genome sequences of <i>Pseudomonas</i> jumbo phages, ΦNK1 and ΦBrmt, from sewage water in Japan. [PDF]
Fujiki J+7 more
europepmc +1 more source
Impact of bioreactor process parameters and yeast biomass on Raman spectra
Abstract In‐line Raman spectroscopy combined with chemometric modeling is a valuable process analytical technology (PAT) providing real‐time quantitative information on cell culture compounds. Considering that compound quantification through chemometric models depends on pre‐processing to maintain consistent changes in intensity at certain wavenumbers,
Maarten Klaverdijk+3 more
wiley +1 more source
Metagenomic insights into microbial diversity and potential pathogenic transmission in poultry farm environments of Bangladesh. [PDF]
Yasmin A+7 more
europepmc +1 more source
ABSTRACT This study describes the green synthesis, characterization, and biological evaluation of silver nanoparticles (AgNPs) obtained from green propolis (AgNPs‐PRO). Before nanoparticles synthesis, a hydroethanolic green propolis extract (GPE) was obtained through ultrasound‐assisted extraction and characterized by high‐performance liquid ...
Erica Tirzah S. Lima+13 more
wiley +1 more source
Impact of heavy metals on antibiotic resistance of Escherichia coli from slum wastewater in Kawempe division, Kampala district, Uganda: a case study. [PDF]
Byarugaba I+3 more
europepmc +1 more source
Microbiological quality of drinking water in urban communities, Rawalpindi, Pakistan
Imran Hashmi+2 more
openalex +1 more source
Promising Prodiginins Biological Activities
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto+6 more
wiley +1 more source
Complete genome sequences of six <i>Serratia</i> strains with multiple resistance genes isolated from food products in Canada. [PDF]
Kang M+5 more
europepmc +1 more source