Results 51 to 60 of about 1,292,283 (312)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Macrocyclic cyanocobalamin (vitamin B12) as a homogeneous electrocatalyst for water oxidation under neutral conditions

open access: yes, 2020
Highly water-soluble cyanocobalamin (also known as vitamin B-12) is the most structurally macrocyclic complex comprising cobalt in the center of a corrin ring.
Ahmad, Nazir   +5 more
core   +1 more source

Kinetic Study of the Electrochemical Mineralization of m-Cresol on a Boron-Doped Diamond Anode. [PDF]

open access: yes, 2012
The kinetics of the electrooxidation of m-cresol in aqueous solution was investigated in a one-compartment flow electrochemical cell with a boron-doped diamond electrode (BDD).
Brillas, Enric   +3 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

How ab initio Molecular Dynamics Can Change the Understanding on Transition Metal Catalysed Water Oxidation

open access: yesCHIMIA, 2021
Artificial water splitting is a promising technology that allows the storage of renewable energy in the form of energy-rich compounds. This mini-review showcases how theoretical studies contribute to the under-standing of existing water oxidation ...
Mauro Schilling   +2 more
doaj   +1 more source

Stainless steel made to rust: a robust water-splitting catalyst with benchmark characteristics [PDF]

open access: yes, 2015
The oxygen evolution reaction (OER) is known as the efficiency-limiting step for the electrochemical cleavage of water mainly due to the large overpotentials commonly used materials on the anode side cause.
Anindita   +78 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A Molecular CO2 Reduction Catalyst Based on Giant Polyoxometalate {Mo368}

open access: yesFrontiers in Chemistry, 2018
Photocatalytic CO2 reduction in water is one of the most attractive research pursuits of our time. In this article we report a giant polyoxometalate {Mo368} based homogeneous catalytic system, which efficiently reduces CO2 to formic acid with a maximum ...
Santu Das   +11 more
doaj   +1 more source

Photochemical behavior of the drug atorvastatin in water. [PDF]

open access: yes, 2006
Atorvastatin undergoes a self-sensitized photooxygenation by sunlight in water. The main photoproducts, isolated by chromatographic techniques, have been identified by spectroscopic means.
CERMOLA, FLAVIO   +5 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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