Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Revegetation in arid zones poses numerous challenges, due particularly to drought, extreme temperatures, high irradiance, and infertile soils, factors which threaten the survival of installed saplings.
María Emilia Fernández +2 more
doaj
Robust Soil Water Potential Sensor to Optimize Irrigation in Agriculture. [PDF]
Menne D +3 more
europepmc +1 more source
Does food trade save water?: the potential role of food trade in water scarcity mitigation [PDF]
Food production / Trade / Water ...
International Water Management Institute (IWMI).
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Polarizable Water Potential Derived from a Model Electron Density. [PDF]
Rackers JA, Silva RR, Wang Z, Ponder JW.
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Stem water potential measurements obtained using standard methodologies diverge under extreme drought in tomato and grapevine. [PDF]
Rodriguez-Dominguez CM +3 more
europepmc +1 more source
Assessing water stress in a high-density apple orchard using trunk circumference variation, sap flow index and stem water potential. [PDF]
Wheeler WD, Black B, Bugbee B.
europepmc +1 more source

