Results 191 to 200 of about 6,486,648 (282)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Should we delay leaf water potential measurements after excision? Dehydration or equilibration? [PDF]

BMC Plant Biol
Perera-Castro AV, Puértolas J, Fernández-Marín B, González-Rodríguez ÁM.   +3 more
europepmc   +1 more source

Validating the Impact of Water Potential and Temperature on Seed Germination of Wheat (Triticum aestivum L.) via Hydrothermal Time Model. [PDF]

Life (Basel), 2022
Saeed S, Ullah A, Ullah S, Noor J, Ali B, Khan MN, Hashem M, Mostafa YS, Alamri S, Alamri S.   +9 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Using long-term field data to quantify water potential regulation in response to VPD and soil moisture in a conifer tree. [PDF]

New Phytol
Bourbia I, Yates LA, Brodribb TJ.
europepmc   +1 more source

The impact of coronavirus SARS-CoV-2 (COVID-19) in water: potential risks. [PDF]

Environ Sci Pollut Res Int, 2021
Girón-Navarro R, Linares-Hernández I, Castillo-Suárez LA.   +2 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Foliar Water Uptake Supports Water Potential Recovery but Does Not Affect Xylem Sap Composition in Two Salt-Secreting Mangroves. [PDF]

Plant Cell Environ
Losso A, Gauthey A, Mayr S, Choat B.
europepmc   +1 more source

Stem girth changes in response to soil water potential in lowland dipterocarp forest in Borneo: An individualistic time-series analysis. [PDF]

PLoS One, 2022
Newbery DM, Lingenfelder M.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source