Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao +10 more
wiley +1 more source
International Water Management Institute success stories 2000-2009 [PDF]
Research institutes / Research projects / Development projects / Water resource management / Water use / Multiple use / Food security / Soil conservation / Poverty / Farmers / Water harvesting / Water storage / Tanks / Land management / Drinking water ...
Chartres, Colin J.
core
Hafnium (Hf)‐rich carbon dots (Hf‐rCDs) with high metal content (40.7%) and robust batch production capacity (>2 g per batch) are synthesized via a facile air‐assisted pyrolysis method. In vivo CT imaging demonstrates outstanding performance of Hf‐rCDs across multiple physiological systems and enables high‐resolution visualization of swine cervical ...
Shuo Li +11 more
wiley +1 more source
Net Gains from Conjunctive Use of Surface and Ground Water [PDF]
Pakistan is fortunate enough because its soils, topography and climate are generally suitable for farming but its agriculture sector faces the problem of scarcity of the irrigation water.
Hugh Turral +2 more
core
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao +16 more
wiley +1 more source
Determining a suitable “dry sowing and wet emergence” water control program for cotton fields in the arid regions of Northwest China is of great significance in saving water resources, improving economic efficiency, and promoting sustainable development ...
Jianqin Ma +8 more
doaj +1 more source
Are low-producing plants sequestering carbon at a geater rate than high-producing plants? : a test within the genus Chionochloa : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Ecology at Massey University, Palmerston North, New Zealand [PDF]
Plant life and primary production play an important role in the global carbon (C) cycle through the fixing of atmospheric C into the terrestrial biosphere. However, the sequestration of C into the soil not only depends on the rate of plant productivity,
Dickson, Matthew Phillip Sijbe
core
Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye +19 more
wiley +1 more source
Improving water productivity: how do we get more crop from every drop [PDF]
Water management / Productivity / Irrigation management / Supplemental irrigation / Crop ...
International Water Management Institute (IWMI) / Comprehensive Assessment of Water Management in Agriculture
core
Direct Recycling of Mixed‐Oxide Cathodes: Balancing Cost, Performance and Environmental Trade‐Offs
Direct regeneration routes for mixed‐oxide lithium‐ion battery cathodes are systematically compared using harmonized techno‐economic, electrochemical, and environmental metrics. Solid‐state, hydrothermal, molten salt, electrochemical, and chemical relithiation methods are benchmarked to identify performance, cost, and sustainability trade‐offs.
Evgenii Beletskii +8 more
wiley +1 more source

