Results 31 to 40 of about 50,562 (264)

Numerical Study on the Effects of Regional Groundwater Flow on the Contaminant Migration through an Inactive Supply Well as a Preferential Flow Pathway

Geofluids, 2022
Preferential flow pathways connect upstream and downstream channels in abandoned mines or seasonally pumping areas. The inactive supply well facilitates contaminant migration between aquifers leading to water quality challenges; it is important to note ...
Xu Li, Shilin Su, Qiang Guo, Haitao Zhang, Qi Zhu, Hamza Jakada   +5 more
doaj   +1 more source

Investigating the Double-Fissure Interactions of Hydraulic Concrete Under Three-Point Bending: A Simulation Study Using an Improved Meshless Method

Buildings
Hydraulic concrete is prone to cracking and interactive propagation under complex stress, threatening its structural integrity and service life. To address limitations of traditional numerical methods (e.g., mesh dependency in FEM) and imprecision of ...
Hua Zhang, Yanran Shi, Dong Niu, Yongqiang Xin, Dunzhe Qi, Bufan Zhang, Wei Li, Shuyang Yu   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Review on Solar Photovoltaic-Powered Pumping Systems

Energies, 2022
Water and energy are becoming more and more important in agriculture, urban areas and for the growing population worldwide, particularly in developing countries.
Levon Gevorkov, José Luis Domínguez-García, Lluis Trilla Romero   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatiotemporal evolution and influencing factors of carbon stock in the water receiving areas from the perspective of carbon neutrality

Scientific Reports
Water resources of water transfer projects are not only used to solve the water scarcity problem in the water-receiving area but also to change the regional carbon absorption capacity. Using the water-receiving area of the Jiangsu-Shandong section of the
Zhuoyue Peng, Mengting Li, Yaming Liu, Junxian Yin, Hongyuan Fang, Jiawei Wen   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Deformation characteristics of sand in confined aquifer under cyclic pumping-recharging groundwater

Yantu gongcheng xuebao, 2018
In order to investigate the influences of artificial recharge and seasonal changes of groundwater levels on deformation characteristics of sand in confined aquifer, using the FlowTrac II system for incremental consolidation testing, the uniaxial ...
LI Ya-jie , WANG Xu-dong , WANG Ya-ping , CHANG Yin-sheng
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source