Results 111 to 120 of about 7,297,851 (384)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Devising an economical water purification unit using bio-adsorbent
Journal of Basic and Applied Research in Biomedicine, 2022 Number of techniques are available to purify water, it include reduction, precipitation, ion exchange, electrochemical reduction and reverse osmosis. Most of them involve high capital costs with recurring expenses, which are not suitable for small-scale
Shivprasad Majumdar +2 more
doaj +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Evaluation of NCA WASH Program in Iraq, 2005-2011 [PDF]
, 2011 After a 14-year history of working in Iraq, Norwegian Church Aid (NCA) began phasing out its operations there in 2011. This evaluation looks at the impact of water supply and desalination units they installed in schools, hospitals, cities and rural ...
Bjørnar Danielsen +1 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Regenerable biocide delivery unit [PDF]
, 1993 A method and apparatus are disclosed for maintaining continuous, long-term microbial control in the water supply for potable, hygiene, and experimental water for space activities, as well as treatment of water supplies on Earth. The water purification is
Colombo, Gerald V. +2 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Optimisation of EDM Process for Water Purification
Chemical Engineering Transactions, 2016 This paper discusses the process of water purification from harmful impurities by using electrical discharge machining (EDM) metal balls in an aqueous solution. The mathematical model has been developed for the water purification process.
I.S. Nadezhdin +3 more
doaj +1 more source
Economies of Vertical Integration in the Japanese Water Supply Industry [PDF]
The merging of some water utilities in Japan has become possible since the 2000 Outline of Administrative Reform and the 2001 Water Act Revision.
Takuya Urakami
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source