Results 111 to 120 of about 628,677 (357)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Characterizing natural separation and purification during rural polluted water self-purification in the Dashi River: a multidimensional approach to DOM and microbial interactions

The self-purification capacity of rivers, a natural analog to engineered separation processes, mitigates pollutants through complex physicochemical and biological interactions.
Graham, Nigel, Sun, Kening, Xie, Jin, Yu, Wenzheng, Liu, Ting   +4 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Cellulose-based water purification using paper filters modified with polyelectrolyte multilayers to remove bacteria from water through electrostatic interactions

, 2018
Filtration is a common way to obtain pure drinking water by removing particles and microorganisms based on size exclusion. Cellulose-based filters are affordable and biobased option for the removal of particles but bacteria are usually too small to be ...
Ek, Monica, Illergård, Josefin,, Henschen, Jonatan, Ottenhall, Anna,, Illergård, Josefin, Henschen, Jonatan,, Ottenhall, Anna, Ek, Monica,   +7 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Factors affecting scale formation in water distribution networks of Semnan city and preventive measures

سلامت و محیط, 2021
Background and Objective: Corrosion and precipitation are important indicators of water quality assessment. The aim of this study was to analyze water stability water in Semnan distribution networks. Materials and Methods: To achieve the purpose, samples
Mahsa Jahangiri-rad, Mohammad Rafiee
doaj  

Physico-Chemical Methods of Water Purification

, 2023
The article describes the methods of water purification. About desalination and desalination of water by distillation, physico-chemical bases of water purification by extraction, physico-chemical bases of water purification by ...
Kushshaeva Marguba Rustam qizi
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Purification Effect of Water Eutrophication Using the Mosaic System of Submerged–Emerged Plants and Growth Response

Plants
Aquatic plants play a crucial role in the sustainable management of eutrophic water bodies, serving as a valuable tool for water purification. However, the effectiveness of using aquatic plants for improving water quality is influenced by landscape ...
Baoliang Chang, Yingchun Xu, Ze Zhang, Xiaowen Wang, Qijiang Jin, Yanjie Wang   +5 more
doaj   +1 more source

Optimisation of EDM Process for Water Purification

Chemical Engineering Transactions, 2016
This paper discusses the process of water purification from harmful impurities by using electrical discharge machining (EDM) metal balls in an aqueous solution. The mathematical model has been developed for the water purification process.
I.S. Nadezhdin, D. Papasidero, A.G. Goryunov, F. Manenti   +3 more
doaj   +1 more source