Results 51 to 60 of about 5,844,146 (288)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Analyzing and Predicting the Agronomic Effectiveness of Fertilizers Derived from Food Waste Using Data-Driven Models

Applied Sciences
This study evaluates and estimates the agronomic effectiveness of food waste-derived fertilizers by analyzing plant yield and the internal efficiency of nitrogen utilization (IENU) via statistical and machine learning models.
Ksawery Kuligowski, Quoc Ba Tran, Chinh Chien Nguyen, Piotr Kaczyński, Izabela Konkol, Lesław Świerczek, Adam Cenian, Xuan Cuong Nguyen   +7 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

The use of marine algae for the removal of Cu²⁺ and Co²⁺ from aqueous solutions

Desalination and Water Treatment
The present work aims to evaluate the effectiveness and efficiency of Chlorella vulgaris as a low-cost biosorbent for the removal of Cu2+ and Co2+ from aqueous solutions. The analyzed biosorbents were characterized by various methods such as FTIR, pHpzc,
Eleonora Sočo, Andżelika Domoń, Dorota Papciak   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Improvement of Phosphorus Removal from Wastewater Through Fermentation of Low-Concentrated Wastewater Sludge and Increased Production of Volatile Fatty Acids

Limnological Review
This article presents the results of a two-stage study: the first stage involved assessing the dependence of the increase or decrease in the concentration of volatile fatty acids (VFAs) on external factors and then assessing the relationship between the ...
Elena Gogina, Nikolay Makisha, Igor Gulshin, Anna Reshetova   +3 more
doaj   +1 more source

Development of a MPC-based Control System for Electrical Discharge of Water Purification Plant

Chemical Engineering Transactions, 2018
The method of electrical discharge of water purification is a complex chemical-technological process. Under the influence of electrical discharges in the water purification plant, chemical processes such as the oxidation of the electroerosion products ...
Igor S. Nadezhdin, Aleksey G. Goryunov, Flavio Manenti   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source