Results 81 to 90 of about 8,064,225 (347)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Improvement of Phosphorus Removal from Wastewater Through Fermentation of Low-Concentrated Wastewater Sludge and Increased Production of Volatile Fatty Acids

Limnological Review
This article presents the results of a two-stage study: the first stage involved assessing the dependence of the increase or decrease in the concentration of volatile fatty acids (VFAs) on external factors and then assessing the relationship between the ...
Elena Gogina, Nikolay Makisha, Igor Gulshin, Anna Reshetova   +3 more
doaj   +1 more source

Development of a MPC-based Control System for Electrical Discharge of Water Purification Plant

Chemical Engineering Transactions, 2018
The method of electrical discharge of water purification is a complex chemical-technological process. Under the influence of electrical discharges in the water purification plant, chemical processes such as the oxidation of the electroerosion products ...
Igor S. Nadezhdin, Aleksey G. Goryunov, Flavio Manenti   +2 more
doaj   +1 more source

Coagulant recovery from water treatment residuals: a review of applicable technologies [PDF]

, 2014
Conventional water treatment consumes large quantities of coagulant and produces even greater volumes of sludge. Coagulant recovery (CR) presents an opportunity to reduce both the sludge quantities and the costs they incur, by regenerating and purifying ...
Jarvis, Peter, Judd, Simon J., Keeley, James   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Ecological trade-offs in shallow lake restoration: Assessing ecosystem responses to aquatic vegetation restoration and biomanipulation strategies against the background of fishing ban

Ecological Indicators
Aquatic vegetation planting is widely regarded as an effective measure to mitigate lake eutrophication. However, under fishing ban conditions, the absence of mechanisms to regulate fish populations may lead to unintended consequences for the lake ...
Tianpeng Chen, Shuo Feng, Yangcun Xie, Kening Wang, Xiaohui Wang, Jinyong Zhao, Jing Zhang   +6 more
doaj   +1 more source

Evaluation of Multifactor Interactions on Water Self-purification Based on Response Surface Methodology and Structural Equation Modeling [PDF]

长江科学院院报
[Objective] This study investigates the synergistic and antagonistic effects of multiple factors on water self-purification capacity and examines self-purification efficiency of water under the combined influence of multiple factors, aiming to overcome ...
ZHANG Yu-jie, YANG Wen-jun
doaj   +1 more source

Water purification using ultrasound waves: application and challenges

Arab Journal of Basic and Applied Sciences, 2020
Due to the scarcity of water resources and the harmful effects of sewage on water bodies, water purification becomes an important issue. The application of ultrasonic waves is a novel technique developed for water purification.
Nashwa A. H. Fetyan, Tamer Mohamed Salem Attia   +1 more
doaj   +1 more source

Quick appraisal of "Sistema de suministro desde el embalse del Cenajo a la Mancomunidad de Canales del Taibilla" [PDF]

, 2013
The project under assessment concerns the construction of an aqueduct in order to divert water from Tajo-Segura Channel onto the Cenajo reservoir and to the water purification plants of Sierra de la Espada and of Campotéjar.
COWI, Directorate-General for Regional and Urban Policy (European Commission)   +1 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source