Results 131 to 140 of about 18,853,489 (341)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Irrigation and water quality [PDF]
Irrigation ; California ; Agriculture - California ; Water-supply ...
Carolyn Sherwood-Call
core
Assessment of the water quality of ten Waikato lakes based on zooplankton community composition. CBER Contract Report No. 60 [PDF]
, 2007 Zooplankton communities were documented from ten Waikato lakes from net haul samples collected in late 2006 and from species hatched from diapausing eggs in sediments collected in early 2007.
Duggan, Ian C.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Quantification of land-use impact on stream water quality [PDF]
, 2002 Accelerated eutrophication of Beaver Lake in northwest Arkansas is a major environmental concern. When developing watershed-management plans to protect lake water quality, it is important that linkages among land-use activities and water quality of ...
Chaubey, Indrajeet +2 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
POLICY ISSUES IN WATER QUALITY [PDF]
Resource /Energy Economics and Policy,
Swader, Fred
core +1 more source
Lake Champlain Water Quality: A Study of Public Awareness, Perceptions, and Behavior [PDF]
, 2016 Introduction: Lake Champlain serves as a major source of drinking water and a prime recreational area in Vermont. The Vermont Department of Health actively monitors Lake Champlain water quality, generates informational resources, and issues restrictions ...
Carney, Jan +9 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source