Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
ECOLOGIC APPROACH TO THE RESTORATION PROCESS AT AREAS DEGRADED BY MINING OPERATIONS [PDF]
, 2018 Donetsk Region belongs to the zone of the most Ukrainian critical ones in provision with water and the quality of water. The main reason of the water quality deterioration is anthropogenic pollution due to untreated water discharge by the region’s ...
Chepak, Olga +2 more
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Modeling and Spatiotemporal Mapping of Water Quality through Remote Sensing Techniques: A Case Study of the Hassan Addakhil Dam [PDF]
, 2021 Anas El Ouali +9 more
openalex +1 more source
Managing nitrogen legacies to accelerate water quality improvement
Nature Geoscience, 2022 N. Basu +12 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
The effects of water quality on freshwater fish populations - final report [PDF]
, 1990 There is a need to determine quantitative relationships between fishery status and water quality in order to make informed judgements concerning fishery health and the setting of environmental quality standards for fishery protection.
Gulson, J., Mainstone, C.P.
core
Water balance computation and water quality improvement evaluation for Yanghe Basin in a semiarid area of North China using coupled MIKE SHE/MIKE 11 modeling [PDF]
, 2021 Ruifen Liu +5 more
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Irrigation Method and Volume for Korla Fragrant Pear: Impact on Soil Water and Salinity, Yield, and Fruit Quality [PDF]
, 2022 Yao Zhang +6 more
openalex +1 more source