Results 161 to 170 of about 5,017,903 (307)

Water quality in reference watersheds in the United States: A compilation and analysis of small watershed data. [PDF]

J Environ Qual
Harmel RD, Amatya D, Sebestyen S, Sun G, Mott J, Schantz M, Boggs J, Caldwell P, Campbell J, Hird A, Keppeler ET, Rau B, Johnson SL, Smith D.   +13 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Increasing riparian vegetation cover to improve water quality: the importance of considering land use. [PDF]

Environ Manage
Te Ngaio PAJ, McMahon JM, van den Berg D, Healy A, Turner RDR, Marsh A.   +5 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Diving into AI? Exploring the Potential for AI to Tackle Complex Water Quality Challenges. [PDF]

Environ Sci Technol
Borgomeo E, Holmes LA, Billari CG, Bitsios I, Brown S, Dickson DJ, Ford E, Fry M, Gaffney J, Garg S, Girona-Mata M, Giuliani M, Hayes N, Hunt LH, Johnson A, Latifi M, Marinoni A, Orr HG, Pemberton E, Rowan-Robinson R, Samadi V, Shepherd W, Sims K, Spooner S, Tlhomole J, Tso CM, Williams T, Xia X.   +27 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Temporal dynamics and analysis of pollutant parameters in the water quality entering a reservoir dam. [PDF]

Sci Rep
Mostafazadeh R, Irani T, Mousavi Moghanjoghi S, Moezzipour B.   +3 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Identification of chemical and physical key water quality drivers in the urban Grunewald Chain of Lakes, Berlin. [PDF]

Sci Rep
Radtke CF, Heinemann N, Höring A, Schröter K.   +3 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source