Results 41 to 50 of about 15,051,160 (301)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Water quality assessment in an arid region using a water quality index

open access: yesWater Science and Technology, 2009
Water quality of the Zayandehrud River, located in an arid region of central part of Iran, was assessed using National Sanitation Foundation Water Quality Index (NSF WQI) calculated by four aggregation methods. Water samples were collected monthly (July 2006 to June 2007) from eight stations in the middle of the river.
M Nemati, Varnosfaderany   +3 more
openaire   +2 more sources

Towards regulatory readiness: evaluating frameworks for microplastic health risk assessment

open access: yesMicroplastics and Nanoplastics
Micro- and nanoplastic particles (MNPs) have emerged as pollutants of high public concern. Assessing and managing the risks of these particles remains challenging for several reasons.
Albert A. Koelmans   +11 more
doaj   +1 more source

Tracing surface and airborne SARS-CoV-2 RNA inside public buses and subway trains

open access: yesEnvironment International, 2021
Given the widespread concern but general lack of information over the possibility of SARS-CoV-2 infection in public transport, key issues such as passenger personal hygiene, efficient air circulation systems, and the effective disinfection of frequently ...
Teresa Moreno   +12 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Water Quality Monitoring and Assessment

open access: yes, 2019
July 1, 2019Executive summary -- Introduction -- Kansas Water Resources -- Surface waters -- Streams and springs -- Lakes and reservoirs -- Wetlands -- Groundwater -- Status of Kansas water quality monitoring programs -- Allocation of duties -- Overview ...
Kansas Department of Health and Environment
core   +1 more source

Estimated health impacts from maritime transport in the Mediterranean region and benefits from the use of cleaner fuels

open access: yesEnvironment International, 2020
Ship traffic emissions degrade air quality in coastal areas and contribute to climate impacts globally. The estimated health burden of exposure to shipping emissions in coastal areas may inform policy makers as they seek to reduce exposure and associated
M. Viana   +8 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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