Results 111 to 120 of about 429,250 (301)
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Oxidative Stress of Cadmium and Lead at Environmentally Relevant Concentrations on Hepatopancreas of Macrobrachium nipponensis and Their Mixture Interactivity: Implications for Water Quality Criteria Amendment. [PDF]
Int J Environ Res Public Health, 2022 Liu X, Deng Q, Yang H, Wang J, Wang M.
europepmc +1 more source
Other title: Water Quality Standards and Supporting Documents
, 2005 "January 28, 2005."; application/pdfThe following pages contain an unofficial version of the most currently effective Kansas Surface Water Quality Standards (K.A.R. 28-16-28b through 28-16-28g), and the standards supporting documents.
Kansas. Bureau of Water.
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
, 2020 The multicomponent composition of wastewater makes it challenging to assess its quality objectively, but the last one is a prerequisite for the safe re-use of wastewater.
Sophia Romanova +4 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
River Water Quality Zoning Using Combination of Principal Component Analysis (PCA) and Fuzzy Clustering Analysis [PDF]
آب و فاضلاب, 2015 Management decisions whose environmental impacts affect directly or indirectly surface waters must of necessity be based on adequate knowledge and information when water quality zoning and a clear picture of river water quality are sought.
Hamidreza Safavi +2 more
doaj
Arthritis Care &Research, EarlyView.Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan +10 more
wiley +1 more source