Results 81 to 90 of about 13,099,362 (290)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Water Quality Notes: What are concentrations and loads, and why do they matter?
EDISWater quality is a broad term used to describe a range of physical, chemical, and/or biological characteristics of water. Many different factors contribute to water quality.
Alexander J. Reisinger +4 more
doaj +3 more sources
Prepared for Public Meeting, Galveston Bay Enforcement Conference, Houston, Texas
, 1972 12 pagesOne result of the Galveston Bay Enforcement Conference was the formation of the Galveston Bay Technical Committee - a committee composed of personnel from the staffs of the Texas Water Quality Board and the EPA.
Texas Water Quality Board
core +2 more sources
Sources of data for water quality criteria [PDF]
Environmental Toxicology and Chemistry, 2013 Susan M, Cormier, Glenn W, Suter
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
401 Water quality certification
Water Boards Water Boards KRI STINE MURRAY, CHAIR I JAYNE J o y, EXECUTIVE OFFICER e GAVIN N EWSOM GOVfA NOR YANA GARCIA SECRETARY FOR ENVIRONMENTAL PROTECTION 3737 Main Street, Suite 500, Riverside, CA 92501-3348 I www.waterboards.ca.gov/santaana Santa ...
California Regional Water Quality Control Board;
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The Application of Reference Dose Prediction Model to Human Health Water Quality Criteria and Risk Assessment. [PDF]
Toxics, 2023 Men SH +6 more
europepmc +1 more source
An ecosystem modelling approach for deriving water quality criteria
Water Science and Technology, 2007 Ecological effects of chemicals on ecosystems are the result of direct effects of the chemical, determined in single-species toxicity testing, and indirect effects due to ecological interactions between species. Current experimental methods to account for such interactions are expensive. Hence, mathematical models of ecosystems have been proposed as an
F, De Laender +3 more
openaire +2 more sources
2004 Texas Water Quality Inventory [PDF]
, 2004 Waller Creek Working ...
Texas Commission on Environmental Quality
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