Results 81 to 90 of about 429,250 (301)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Quality Characterization of Groundwater for Drinking Purposes and Its Network Distribution to Assure Sustainability in Southern Region of Saudi Arabia

, 2022
Water demand per capita will rise in the Arab world as a result of climate change and population expansion. One of the most important aims in coping with population increase around the world is to conserve water supplies.
Tarek A. Abdou, Saad M. Alramthi, Ahmed M. Shaban, Saad H. Eldosari, Bao-Ku Zhu, Gamila H. Ali, Atiah M. Elthagafi, Hosam M. Safaa   +7 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Water Quality Notes: What are concentrations and loads, and why do they matter?

EDIS
Water quality is a broad term used to describe a range of physical, chemical, and/or biological characteristics of water. Many different factors contribute to water quality.
Alexander J. Reisinger, Andrea Albertin, Eban Bean, Ashley Smyth, P. Christopher Wilson   +4 more
doaj   +3 more sources

Multi-criteria decision analysis for integrated water quality assessment and management support

Water Research X, 2018
In densely populated areas, surface waters are affected by many sources of pollution. Besides classical pollutants like nutrients and organic matter that lead to eutrophication, micropollutants from various point- and non-point sources are getting more ...
Nele Schuwirth, Mark Honti, Ivana Logar, Christian Stamm   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Report on water quality survey and pollution in Kurunegala, Sri Lanka [PDF]

Water resources / Water pollution / Water quality / Monitoring / Electrical conductivity / Ph / Nitrogen / Iron / Boron / Heavy metals / Coliform bacteria / Sri Lanka / Kurunegala / Wan Ela / Beu ...
Clemett, Alexandra, Dissanayake, Priyanka, Jayakody, Priyantha, Amerasinghe, Priyanie   +3 more
core  

GIS, Multivariate Statistics Analysis and Health Risk Assessment of Water Supply Quality for Human Use in Central Mexico

, 2021
The spatial assessments of water supply quality from wells, springs, and surface bodies were performed during the dry and rainy seasons in six municipalities in the eastern regions of Michoacán (Central Mexico).
Leonel Hernández-Mena, José de Jesús Díaz-Torres, Reyna Lizette Pacheco-Domínguez, Erick R. Bandala, Ramiro Vallejo-Rodríguez, María Guadalupe Panduro-Rivera, Valeria Ojeda-Castillo, Ofelia Morton-Bermea, Rogelio Santacruz-Benítez, Malaquías López-Cervantes, Daryl Rafael Osuna-Laveaga, Jorge del Real-Olvera, Valentín Flores-Payán   +12 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source