Results 111 to 120 of about 1,634,541 (309)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Evaluation of solar powered water pumping system: the case study of three selected Abattoirs in Ibadan, Nigeria

International Journal of Sustainable Engineering, 2019
In this paper, detailed and comprehensive analysis of the technical, environmental and economic benefits of providing adequate water supply using solar PV system for three selected abattoirs (Bodija, Akinyele and Iyana church abattoirs) in Ibadan are ...
Temitope Raphael Ayodele, Ayodeji Samson Olatunji Ogunjuyigbe, Omolola Anuoluwa Adeniran   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Effects of crop evapotranspiration estimation techniques and weather parameters on rice crop water requirement [PDF]

, 2014
Accurate estimation of crop evapotranspiration is key to determination of crop water requirements as well as water productivity. In this study, Microflex-C sensors were mounted on three sets of lysimeter to measure crop evapotranspiration in the paddy ...
Abd Aziz, Samsuzana, Abdullah, Mohd Yazid, Kamal, Md. Rowshon, Mamodu, Maina Mohammed, Mohd Soom, Mohd Amin, Wayayok, Aimrun   +5 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Optimal Policies for Conjunctive-Use and Cropping Pattern for Al-Wand Basin

مجلة النهرين للعلوم الهندسية, 2017
Applying conjunctive use between surface water and ground water is getting widely used at many regions in the world, due to the increasing need of water resources, especially when large quantities of water and for long time are used for irrigation ...
Amer Hassan Al-Haddad, Zainab Kadhim Jabal   +1 more
doaj  

A Method for the Rapid Cultivation of Desulfovibrio aestuarii on Filter Membranes [PDF]

, 1958
The cultivation of sulfate-reducing bacteria on agar plates is a somewhat involved and time-consuming process. This is partly due to the requirement for fairly strict anaerobic conditions but mainly because of the length of the incubation period which ...
Goetz, A., Tsuneishi, N.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Faktor-faktor yang Berhubungan dengan Kualitas Bakteriologis Sumur Gali di Kelurahan Jatibarang Kecamatan Mijen Kota Semarang [PDF]

, 2003
Air penting bagi kehidupan, kebutuahn manusia akan air sangat kompleks antara lain untuk keperluan minum, masak, mandi dan mencuci. Persyaratan kualitas air di atur dalam peraturan pemerintah RI nomor 82 tahun 2001 tentang pengelolaan kualitas air dan ...
Sila, OKtofianus
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source