Results 121 to 130 of about 1,634,541 (309)
Water Pricing Models: a survey [PDF]
This paper surveys water pricing models, highlighting some important results. Efficiency rquires marginal cost pricing. Intra-annual price changes or customer differentiation to reflect differences in marginal costs can enhance efficiency.
Henrique Monteiro
core
A modeling of the carbon-nitrogen cycle transport at Igap\'o I Lake - Londrina, Paran\'a, Brazil
, 2010 This work is a contribution to better understand the effect that domestic sewage discharges may cause in a water body, specifically Igap\'o I Lake, in Londrina, Paran\'a, Brazil.
Cirilo, Eliandro Rodrigues +3 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
علوم آب و خاک, 2019 Estimation of evapotranspiration is essential for planning, designing and managing irrigation and drainage schemes, as well as water resources management. In this research, artificial neural networks, neural network wavelet model, multivariate regression
N. Ganji khorramdel, S. M. R. Hoseini
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Change of crop structure intensified water supply-demand imbalance in China’s Black Soil Granary
Agricultural Water ManagementChanges of crop planting area and structure generally cause much uncertainty in water sustainability. As the main grain producing area in China, the Black Soil Granary area (covering the whole Songhua River Basin) is facing the contradiction between ...
Ying Feng +5 more
doaj +1 more source
Gender in Water and Sanitation [PDF]
, 2010 The report highlights the experiences of mainstreaming gender at various levels in the water and sanitation sector. It begins with a discussion on gender responses to policy and its requirement for analysis and clear policy objectives to guide operations.
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Silver-based Microbial Check Valve for Spacecraft Potable Water Systems [PDF]
, 2019 As human space exploration increases, the development of a more efficient potable water treatment system suited for spacecraft becomes crucial. This Waste-management Education Research Consortium (WERC) challenge was designed to explore the viability of ...
Garcia, Rogelio E
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source