Results 251 to 260 of about 1,378,017 (305)

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

Correction: Transcriptome analysis of <i>Pseudomonas syringae</i> pv. tomato DAPP-PG 215 in response to silver nanoparticles exposure. [PDF]

Front Microbiol
Orfei B, Pothier JF, Scotti L, Aceto A, Moretti C, Buonaurio R, Smits THM.   +6 more
europepmc   +1 more source

Chemical Upcycling of Polyphenylene Sulfide at Room Temperature

Advanced Science, EarlyView.
Poly(phenylene sulfide) (PPS) is a semi‐crystalline super engineering plastic with exceptional properties. An iron‐photocatalyzed strategy is reported for chemical upcycling of PPS plastics at room temperature using 1,2‐dichloroethane. The method demonstrates remarkable efficiency across diverse PPS resins and post‐consumer composites, even within ...
Boning Gu, Chengliang Li, Xuefeng Jiang
wiley   +1 more source

New frontiers for unmanned aerial vehicles in planetary health research. [PDF]

BMC Glob Public Health
Bramante JT, Tarpenning MS, Woo KE, Chamberlin AJ, Coombe KD, Rosser JI.   +5 more
europepmc   +1 more source

Oral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis

Advanced Science, EarlyView.
Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.
Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li   +13 more
wiley   +1 more source

Scaled decentralization for sustainable wastewater treatment in high-density cities. [PDF]

Environ Sci Ecotechnol
Abulimiti A, Wang B, Wang X, Ren N.
europepmc   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Spatiotemporal Root-Trait Plasticity Underpins Almond Yield Stability and Enhanced Water and Nitrogen Use Efficiency Under Prolonged Fertigation Reduction. [PDF]

Plants (Basel)
Zhou S, Lawlor A, Walker RR, Edwards EJ.
europepmc   +1 more source

Asymmetry of safeguarding regional air and water nitrogen boundaries in China. [PDF]

Natl Sci Rev
Zou Y, Zhang X, Xu X, Wu J, Cheng L, Xu X, Deng O, Chen Y, Wang C, He P, Wang S, Wang M, Winiwarter W, Gu B.   +13 more
europepmc   +1 more source

Smart irrigation-based internet of things and cloud computing technologies for sustainable farming. [PDF]

Sci Rep
Morchid A, Qjidaa H, Alami RE, Mobayen S, Skruch P, Bossoufi B.   +5 more
europepmc   +1 more source