Results 41 to 50 of about 1,378,017 (305)

Privatization of Water Resource Management in the Discourse of Local Government Autonomy [PDF]

, 2021
Water is an inseparable element of human life. Data from National Geographic shows that Indonesia holds 6% of the world’s water supply or about 21% of Asia Pacific water supply. Indonesia’s potential water resource reserves are around 3,900 billion cubic
Al-Fatih, Sholahuddin, Anggraeny, Isdian, Esfandiari, Fitria, Hidayah, Nur Putri, Lutfi, M   +4 more
core   +1 more source

A critical review of resource recovery from municipal wastewater treatment plants : market supply potentials, technologies and bottlenecks [PDF]

, 2020
In recent decades, academia has elaborated a wide range of technological solutions to recover water, energy, fertiliser and other products from municipal wastewater treatment plants.
Dewulf, Jo, Garfí, Marianna, Kehrein, Philipp, Osseweijer, Patricia, Posada, John, van Loosdrecht, Mark   +5 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Assessment of Forty-Five Bambara Groundnut (Vigna subterranea) Accessions Under Varying Environments in Kenya Using Morphological and Yield Components

International Journal of Agronomy
Understanding the agromorphological diversity of Bambara groundnut is crucial in enhancing its adaptability and productivity in Kenya, where production is localized to a few areas.
Mercy Chelangat, Bernard M. Gichimu, Phyllis W. Muturi, Josiah N. Gitari   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

How reliable are estimates of trace contaminants in rivers based on monthly grab samples?

Environmental Sciences Europe
Background Water quality assessment must rely on representative samples, but obtaining them is increasingly challenging given the growing number and diversity of trace contaminants emitted into water bodies.
Nikolaus Weber, Jounes Lutterbach, Christine Hufnagl, Ernis Saracevic, Steffen Kittlaus, Katarina Kozlica, Radmila Milačič Ščančar, Jörg Krampe, Matthias Zessner, Ottavia Zoboli   +9 more
doaj   +1 more source

IPA (v1): a framework for agent-based modelling of soil water movement [PDF]

Geoscientific Model Development, 2018
In the last decade, agent-based modelling (ABM) became a popular modelling technique in social sciences, medicine, biology, and ecology. ABM was designed to simulate systems that are highly dynamic and sensitive to small variations in their ...
B. Mewes, A. H. Schumann
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Modeling the spatio-temporal flow dynamics of groundwater-surface water interactions of the Lake Tana Basin, Upper Blue Nile, Ethiopia

Hydrology Research, 2020
The Ethiopian government has selected Lake Tana basin as a development corridor due to its water resources potential. However, combined use of groundwater (GW) and surface water (SW) is still inadequate due to knowledge gaps about the flow dynamics of GW
Tibebe B. Tigabu, Paul D. Wagner, Georg Hörmann, Nicola Fohrer   +3 more
doaj   +1 more source

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source