Results 251 to 260 of about 6,910,387 (297)

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Water security

2021
Abstract Today, the concept of security manifests itself in a number of forms in most scientific, social, environmental, and political issues. One of the most essential and prominent types of security issue faced today is water security, which has introduced a complex and new concept to the literature of today's world.
Sahar Baghban, Omid Bozorg-Haddad, Ronny Berndtsson   +2 more
openaire   +2 more sources

Water and Security

2021
The connections between a clean and accessible water supply for consumption and sanitation is a relatively new field of research. Prior to this recognition, scholars and policy analysts associated security with the protection of a nation’s borders and populations. Security implied a nation’s safety in military and diplomatic terms.
David A. Pietz, Dorothy Zeisler-Vralsted
openaire   +1 more source

Water (in)security: securing the right to water

The Geographical Journal, 2014
This paper rereads debates over water security and insecurity through the tools of critical geographical scholarship. It seeks to demonstrate the value of such a critical perspective in achieving access to water for all. While rejecting a simplistic dismissal of mainstream discourses on water security, the paper notes the failure to adequately ...
openaire   +1 more source

Security of Water Infrastructure Systems

2009
This paper formulates the security problem in critical water infrastructure systems for diagnosing quality faults. The proposed scheme is based on the discretized equations of advection and reaction of contaminant concentrations in pipes and tanks, expressed in a state-space form.
Eliades, D. G., Polycarpou, Marios M., Eliades, D. G., Polycarpou, Marios M.   +3 more
openaire   +3 more sources

Water Security, Food Security and the National Water Dependency

2018
Water requirements for food demand in Tunisia have more than tripled over the past four decades, and amount to more than 16 km3 in 2010. As the population has nearly doubled during the same period, water requirements for individual dietary recorded an increase from about 1050 m3/year/capita in the early 1970s to nearly 1600 m3/year/capita in the late ...
Mustapha Besbes, Jamel Chahed, Abdelkader Hamdane   +2 more
openaire   +1 more source

Water Security or Security of Water? A Conceptual Analysis

India Quarterly: A Journal of International Affairs, 2011
The present article tries to understand the concept of water security. What is the threshold beyond which water qualifies to be a security issue? Do our security concerns emanate from the conflictual interests emanating from demand and supply, riparian rights of the intra- or inter-state actors or the ownership of the resource?
openaire   +1 more source