Results 21 to 30 of about 1,457,459 (303)

Comprehensive evaluation and stability analysis of ecosystem quality of Yellow River Basin during 1980–2019

open access: yesRiver, 2023
Quality and stability are the basic characteristics of ecosystems, reflecting their structure, process, functional integrity, ability to resist disturbance, self‐regulation, and dynamic balance.
Zhiwei Cao   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Deriving the Terrestrial Water Storage Anomaly From GRACE Spherical Harmonic Coefficients Using a Convolutional Neural Network

open access: yesEarth and Space Science, 2023
Terrestrial water storage anomaly (TWSA), derived from Gravity Recovery and Climate Experiment (GRACE) satellites, has been widely used in hydrology studies.
Qingquan Zhang   +3 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Study on the effects of hydrological connectivity on the dispersal and driving factors of macroinvertebrate communities

open access: yesScientific Reports
Dispersal is crucial for the distribution of macroinvertebrate populations and communities. However, research on the dispersal of macroinvertebrates after dam demolition remains limited. Studying the impact processes and driving factors of dam demolition
Yuhang Zhang   +6 more
doaj   +1 more source

Urban Water Security Dashboard: Systems Approach to Characterizing the Water Security of Cities [PDF]

open access: yesJournal of Water Resources Planning and Management, 2018
Urban water security is a major concern in the context of urbanization and climate change. Water security goes beyond having good infrastructure or good governance. Systems thinking can help in understanding the mechanisms that influence the long-term water security of a city.
Kees C.H. van Ginkel   +3 more
openaire   +2 more sources

Can a change in cropping patterns produce water savings and social gains: A case study from the Fergana Valley, Central Asia [PDF]

open access: yes, 2018
The study examines possible water savings by replacing alfalfa with winter wheat in the Fergana Valley, located upstream of the Syrdarya River in Central Asia.
Abdurakhmannov, Botir   +3 more
core   +1 more source

Analysis of the performance of a virtual gauge-based method in hydrological modeling of basins with no precipitation stations

open access: yesScientific Reports
This study evaluates the hydrological performance of the virtual gauge-based method (VG) for flood forecasting in basins devoid of precipitation stations.
Yanhong Dou   +4 more
doaj   +1 more source

The complete mitogenome of Chrysopogon zizanioides (L.) Roberty (Poaceae), with its phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2022
Vetiver grass (Chrysopogon zizanioides), is a perennial and tussock C4 grass from the genus Chrysopogon of Poaceae, which has been widely used as a natural and inexpensive resource for multifarious environmental applications. The complete mitogenome of C.
Shuqiong Yang   +6 more
doaj   +1 more source

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