Results 181 to 190 of about 3,541,761 (309)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

OsFLN2 gene knockout reduces leaf water status and photosynthetic performance of rice plants under water deficit. [PDF]

open access: yesBMC Plant Biol
Contiliani DF   +8 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Disentangling the Roles of Plant Water Status and Stem Carbohydrate Remobilization on Rice Harvest Index Under Drought. [PDF]

open access: yesRice (N Y), 2023
Dwivedi SK   +5 more
europepmc   +1 more source

Relationship between soil water status, predawn leaf water potential and other indicators of the plant water status in maize

open access: yes, 1990
Des indicateurs de l’état hydrique du sol (potentiel hydrique dans la zone racinaire et réserve en eau utilisée) ont été mis en relation avec plusieurs indicateurs de l’état hydrique de plantes de maïs pendant la période post-floraison : le potentiel foliaire au lever du jour, le potentiel foliaire pendant la journée, la conductance stomatique et le ...
Tardieu, Francois   +2 more
openaire   +1 more source

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