Results 211 to 220 of about 9,328,709 (366)
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Sewerage and Health: Influence of Sewerage and Water-Supply on the Death-Rate in Cities . By E. F. Smith. Lansing, State, 1885. 8°. [PDF]
J. I. Royce
openalex +1 more source
Learning Lessons: Urban Water Supply Sector [PDF]
Complementing a November 2009 guidance note that outlined risks to development effectiveness in the urban water supply sector, this brief provides relevant lessons from evaluations of Asian Development Bank programs over the last ten years.
core
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
As the scale of water conservancy projects continues to expand, the amount and complexity of analytical data have also correspondingly increased. At present, it is difficult to realize project management decision support based on a single data source ...
Zhen Liu+4 more
doaj +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Korea-Namgang and Taegu water supply project [PDF]
노트 : This document has a restricted distribution and may be used by recipients only in the performance of their official duties.
The World Bank(Urban and Water Supply Division, East Asia and Pacific Projects Department)
core
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source