Results 171 to 180 of about 2,632,519 (299)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Ameliorating effect of zinc on water transport in rice plants under saline-sodic stress. [PDF]

Front Plant Sci
Dang K, Tian H, Bai J, Fu P, Cui J, Ji D, Shao X, Geng Y, Zhang Q, Guo L.   +9 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Role of aquaporins in brain water transport and edema. [PDF]

Front Neurosci
Li Y, Wang Y, Huang X, Zhang H, Guan Y, Zhang X.   +5 more
europepmc   +1 more source

Functional Polymer Nanocomposites with Increased Anticorrosion Properties and Wear Resistance for Water Transport. [PDF]

Polymers (Basel), 2023
Buketov A, Sapronov O, Klevtsov K, Kim B.   +3 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Nodular networks in hydrated polyamide desalination membranes enhance water transport. [PDF]

Sci Adv
Li D, Liu W, Wang X, Lin W, Zhai J, Fan H, Xiao K, Wang K, Li Y, Jin Y, Fang J, Shen Y, Elimelech M, Huang X.   +13 more
europepmc   +1 more source

Capillary-Driven Water Transport by Contrast Wettability-Based Durable Surfaces. [PDF]

ACS Appl Mater Interfaces, 2023
Dimitriadis T, Stendardo L, Tagliaro I, Coclite AM, Antonini C, Maitra T.   +5 more
europepmc   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

The role of pyrope garnet in water transport into the topmost lower mantle. [PDF]

Natl Sci Rev
Chen L, Zhao X, Xu C, Li X, Zhang X, Feng B, Hu K, Liu B, Liu Z, Xu W.   +9 more
europepmc   +1 more source