Results 291 to 300 of about 8,365,932 (359)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Ameliorative effects of biofertilizers on yield, water use efficiency and quality of bean under drought stress conditions. [PDF]

BMC Plant Biol
Demir H, Kaman H, Saka AK, Uçan U, Kotan R, Akgün İH.   +5 more
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Application of various agricultural practices on sorghum forage yield and its association with water use efficiency under deficit irrigation conditions. [PDF]

Sci Rep
Nahed NE, Attia MA, El-Hashash EF, El-Absy KM, El-Shaer HM, Youssef AMA, Sallam SMA, Khafaga HS, Fi A, Abd-Elatty SAA.   +9 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Ecotypic Variation in Photosynthesis, Stomatal Conductance, and Water Use Efficiency of <i>Illicium lanceolatum</i> in Response to Light Intensity Under Drought and Recovery. [PDF]

Plants (Basel)
Cao Y, Zhou B.
europepmc   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Large Variations in the Transpiration of Sorghum Canopies Under High Evaporative Demand Are Positively Related to Water Use Efficiency. [PDF]

Plant Cell Environ
Pilloni R, Aparna K, El Ghazzal Z, Kar S, Hajjarpoor A, Xue W, Affortit P, Ribière W, Badji R, Sine B, Kholova J, Tardieu F, Vadez V.   +12 more
europepmc   +1 more source

Drip fertigation improves cumin productivity, essential oil content, water use efficiency and profitability in arid zones of Rajasthan. [PDF]

Sci Rep
Singh R, Harisha CB, Choudhary S, Ravi Y, Meena NK, Meena RS, Kumar S, Verma AK.   +7 more
europepmc   +1 more source

Water use efficiency of Cupressus gigantea is higher in mountain slope habitats compared to riverside habitats. [PDF]

PLoS One
Jiang Y, Luan L, Zuo Y, Liu S, He Q, He J, Wu R, Jiang G, Liu M.   +8 more
europepmc   +1 more source