Results 41 to 50 of about 3,027,631 (309)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
An Optical Classification Tool for Global Lake Waters
Shallow and deep lakes receive and recycle organic and inorganic substances from within the confines of these lakes, their watershed and beyond. Hence, a large range in absorption and scattering and extreme differences in optical variability can be found
M. Eleveld +5 more
semanticscholar +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Sedimentation and lithological structure of the surface sedimentary strata in the shallow estuary of the River Grendalen (Gren-fjord) [PDF]
This paper presents the results of studies of the River Grendalen estuary shallow (Gren-fjord). It is based on materials of the field work carried out in 2014.
Meshcheryakov N. I., Tarasov G. A.
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The urgency of the conducted studies is dictated by the problem of Urban Territories’ sub-surface waters purification providing in the Republic of Sakha (Yakutia) population with drinking water, which can be partly solved by involving the sub-surface ...
Fedorova Svetlana, Kryzhanovsky Anatolii
doaj +1 more source
Uncharted waters: the rise of human-made aquatic environments in the age of the “Anthropocene”
Anthropogenic global change, including direct alteration of landscapes and rapid shifts in climate, is impacting existing aquatic resources negatively, but it is also giving rise to new water bodies.
Émilie Saulnier‐Talbot, I. Lavoie
semanticscholar +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Geochemical study of Recoaro Terme and Valli del Pasubio area mineral springs (Vicenza Pre-Alps)
[Article in Italian] The mineral waters of the Vicenza Prealps - “Piccole Dolomiti” area, including the basins of the Agno and Leogra streams (Vicenza province), have been characterized from a geochemical point of view.
Gianpiero Brozzo
doaj +1 more source

