Results 141 to 150 of about 562,443 (296)
Enhancing climate resilience through resource conservation practices in watershed of Western India
Frontiers in Sustainable Food SystemsIn the areas affected by soil erosion and water scarcity, watershed management involves all aspects of land and water resources for sustainable development.
Gaurav Singh +11 more
doaj +1 more source
Preliminary Study on Baseflow Separation at Watersheds in East Java Regions
, 2016 Indarto Indarto +2 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
River water quality modelling in Barito watershed
, 2019 Roh Santoso Budi Waspodo +1 more
openalex +1 more source
The application of hydrometeorological data obtained by remote sensing techniques for multipurpose reservoir operations [PDF]
Watershed snowpack and streamflow data obtained and transmitted by (ERTS) satellite were used in the operational and water management decisions in the Salt River Project.
Kirdar, K. +2 more
core +1 more source
Toward improved streamflow forecasts: Value of semidistributed modeling [PDF]
, 2001 The focus of this study is to assess the performance improvements of semidistributed applications of the U.S. National Weather Service Sacramento Soil Moisture Accounting model on a watershed using radar-based remotely sensed precipitation data ...
Boyle, DP +5 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Sustainable Practices in Watershed Management: Global Experiences [PDF]
Watershed management is considered by scholars as well as practitioners across the world as the most appropriate approach to ensure the preservation, conservation and sustainability of all land based resources and for improving the living conditions of ...
Menon, Sudha
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source